SCHEMBL4088445

SCHEMBL4088445

Fc1cc(F)c(O[Zn])c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25987330 0.77 CES2 (0.32) CES2CES1ALDH1A1CA12CA1
SCHEMBL6871667 0.74 CES2 (0.31) CES2CES1
SCHEMBL13863864 0.73 CES2 (0.33) CES2CES1ALDH1A1CA12CA1
SCHEMBL443414 0.71 CES2 (0.32) CES2CES1ALDH1A1CA12CA1
SCHEMBL27540054 0.71 TGM2 (0.32) CES2CES1ALDH1A1CA12CA1
SCHEMBL27243487 0.71 ERN1 (0.34) CES2CES1ALDH1A1CA12CA1
SCHEMBL443415 0.71 PDGFRB (0.39) ALDH1A1CA9
SCHEMBL27510752 0.69 CES2 (0.31) CES2CES1
SCHEMBL4081700 0.69 CES2 (0.31) CES2CES1
Hydrochloric Acid SCHEMBL28754221 0.67 CES2 (0.30) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2048168-A2 Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048170-A2 Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048167-A2 First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048169-A2 Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed