SCHEMBL4089564

SCHEMBL4089564

CCOC(=O)C(CCCCCBr)C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
L3MBTL1 Q9Y468 5/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 3/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
CPB2 Q96IY4 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
TRPA1 O75762 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.39
POLB P06746 1/20 0.38
PTPN1 P18031 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10792134 1.00 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL9695685 1.00 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL9328294 1.00 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL1702872 1.00 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL9697656 1.00 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL1703436 1.00 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL550000 1.00 TDP1 (0.47) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL15727419 0.98 TDP1 (0.49) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL550001 0.92 TDP1 (0.45) TDP1KMT2AMEN1L3MBTL1MAPT
SCHEMBL27877640 0.92 TDP1 (0.45) TDP1KMT2AMEN1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109972691-A Comprehensive rainwater utilization device 徐州工程学院 2019-07-05 CN claimed
CN-109876539-A Automatic rainwater purifying device 徐州工程学院 2019-06-14 CN claimed
CN-109853666-A Rainwater water storage device and control method thereof 徐州工程学院 2019-06-07 CN claimed
CN-109826280-A Efficient rainwater recycling system 徐州工程学院 2019-05-31 CN claimed
CN-109811826-A Rainwater drainage device 徐州工程学院 2019-05-28 CN claimed
CN-109804897-A Intelligent rainwater gathering device 徐州工程学院 2019-05-28 CN claimed
CN-109763537-A Rainwater recycling equipment 徐州工程学院 2019-05-17 CN claimed
CN-109972691-A Comprehensive rainwater utilization device 徐州工程学院 2019-07-05 CN disclosed
CN-109876539-A Automatic rainwater purifying device 徐州工程学院 2019-06-14 CN disclosed
CN-109868864-A Gravity type rainwater collecting and discarding device 徐州工程学院 2019-06-11 CN disclosed
CN-109853666-A Rainwater water storage device and control method thereof 徐州工程学院 2019-06-07 CN disclosed
CN-109853665-A Intelligent integrated rainwater purification equipment 徐州工程学院 2019-06-07 CN disclosed
CN-109826280-A Efficient rainwater recycling system 徐州工程学院 2019-05-31 CN disclosed
US-20050065066-A1 comprising insulin and novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer; physical and chemical stability NOVO NORDISK A/S (DK) 2005-03-24 US disclosed
WO-2004080481-A1 NOVEL NPH INSULIN PREPARATIONS NOVO NORDISK A/S (DK) 2004-09-23 WO disclosed
WO-2004080480-A1 PHARMACEUTICAL PREPARATIONS COMPRISING ACID-STABILISED INSULIN NOVO NORDISK A/S (DK) 2004-09-23 WO disclosed
WO-2004056347-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER NOVO NORDISK A/S (DK) 2004-07-08 WO disclosed
US-6011152-A REACTING STOICHIOMETRIC AMOUNTS OR MORE OF AN AMINO CARBOXYLIC ACID OR A PROTECTED/ACTIVATED FOR THEREOF WITH AN ACTIVATED DERVATIVE SELECTED FROM THE GROUP CONSISTING OF OXALATES AND MALONATES IN THE PRESENCE OF A SOLVENT AND HEAT CARNEGIE MELLON UNIVERSITY (US) 2000-01-04 US disclosed
US-4110412-A Difunctional terminated macromolecular monomers and condensation copolymers produced therefrom CPC INTERNATIONAL INC. (US) 1978-08-29 US disclosed
US-4068050-A Difunctional terminated macromolecular monomers and condensation copolymers produced therefrom CPC INTERNATIONAL INC. (US) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065066-A1 comprising insulin and novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer; physical and chemical stability IAPP, IRS1, INSR TDP1 4842/4885KMT2A 4420/4885MEN1 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.