Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792134 | 1.00 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL9695685 | 1.00 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL9328294 | 1.00 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL1702872 | 1.00 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL9697656 | 1.00 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL4089564 | 1.00 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL550000 | 1.00 | TDP1 (0.47) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL15727419 | 0.98 | TDP1 (0.49) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL550001 | 0.92 | TDP1 (0.45) | TDP1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL27877640 | 0.92 | TDP1 (0.45) | TDP1KMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448509-B1 | Method of preparing phenoxy alkanoic acids and salts thereof via a dicarboxylate intermediate | EMISPHERE TECH INC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-1284724-B1 | METHOD OF PREPARING ALKYLATED SALICYLAMIDES VIA A DICARBOXYLATE INTERMEDIATE | EMISPHERE TECH INC (US) | 2012-04-18 | — | — | EP | disclosed |
| US-7411084-B2 | Method of preparing phenoxy alkanoic, alkenoic, and alkynoic acids and salts thereof via a dicarboxylate intermediate | EMISPHERE TECHNOLOGIES, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| EP-1284724-A4 | METHOD OF PREPARING ALKYLATED SALICYLAMIDES VIA A DICARBOXYLATE INTERMEDIATE | EMISPHERE TECH INC (US) | 2007-10-17 | — | — | EP | disclosed |
| US-7262325-B2 | Method of preparing salicylamides | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-7169776-B2 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169776-B2 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-20060084646-A1 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-04-20 | — | — | US | disclosed |
| EP-1448509-A4 | METHOD OF PREPARING PHENOXY ALKANOIC, ALKENOIC, AND ALKYNOIC ACIDS AND SALTS THEREOF VIA A DICARBOXYLATE INTERMEDIATE | EMISPHERE TECH INC (US) | 2006-02-08 | — | — | EP | disclosed |
| US-6900344-B2 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040171865-A1 | Method of preparing phenoxy alkanoic, alkenoic, and alkynoic acids and salts thereof via a dicarboxylate intermediate | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2004-09-02 | — | — | US | disclosed |
| EP-1448509-A2 | METHOD OF PREPARING PHENOXY ALKANOIC, ALKENOIC, AND ALKYNOIC ACIDS AND SALTS THEREOF VIA A DICARBOXYLATE INTERMEDIATE | Emisphere Technologies, Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20030216593-A1 | Method of preparing salicylamides | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-11-20 | — | — | US | disclosed |
| US-20030096992-A1 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-05-22 | — | — | US | disclosed |
| WO-2003026582-A2 | METHOD OF PREPARING PHENOXY ALKANOIC, ALKENOIC, AND ALKYNOIC ACIDS AND SALTS THEREOF VIA A DICARBOXYLATE INTERMEDIATE | EMISPHERE TECHNOLOGIES INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| EP-1284724-A1 | METHOD OF PREPARING ALKYLATED SALICYLAMIDES VIA A DICARBOXYLATE INTERMEDIATE | Emisphere Technologies, Inc. (US) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092206-A1 | METHOD OF PREPARING SALICYLAMIDES | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| WO-2001070219-A1 | METHOD OF PREPARING ALKYLATED SALICYLAMIDES VIA A DICARBOXYLATE INTERMEDIATE | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171865-A1 | Method of preparing phenoxy alkanoic, alkenoic, and alkynoic acids and salts thereof via a dicarboxylate intermediate | ALK, APEH, ALKBH3 | TDP1 3600/4885KMT2A 2609/4885MEN1 3178/4885 |
| US-20060084646-A1 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate | ADSL, AADAC, SLC16A7 | TDP1 2411/4885KMT2A 2293/4885MEN1 2971/4885 |
| US-20030096992-A1 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate | ADSL, AADAC, SLC16A7 | TDP1 2411/4885KMT2A 2293/4885MEN1 2971/4885 |
| US-20030216593-A1 | Method of preparing salicylamides | SCLY, ADSL, SIK3 | TDP1 3446/4885KMT2A 1129/4885MEN1 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.