Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 12/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094981 | 0.86 | TRPV3 (0.41) | TRPV3HTR2AHTR2CHTR2BCTSS | |
| SCHEMBL3202062 | 0.86 | HTR2A (0.41) | TRPV3HTR2AHTR2CHTR2BCTSS | |
| SCHEMBL4685144 | 0.81 | TLR8 (0.42) | TRPV3PDE2ACTSSCTSKPTGS2 | |
| SCHEMBL5016834 | 0.79 | CTSS (0.39) | TRPV3CTSSCTSKPTGS2RAD51 | |
| SCHEMBL4682811 | 0.77 | TLR8 (0.41) | TRPV3CTSSCTSKPTGS2RAD51 | |
| SCHEMBL5023766 | 0.76 | KCNJ6 (0.40) | TRPV3PTGS2RAD51 | |
| SCHEMBL4089679 | 0.74 | HTR2A (0.33) | TRPV3HTR2AHTR2CHTR2BPTGS2 | |
| SCHEMBL4089570 | 0.74 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL5023843 | 0.73 | TLR8 (0.40) | TRPV3CTSSCTSKPTGS2RAD51 | |
| SCHEMBL29050038 | 0.73 | HDAC6 (0.41) | TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1854784-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | PPARG, PPARA, PPARD | TRPV3 1449/4885HTR2A 2656/4885HTR2C 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.