Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.72 |
| ▸ | CDK2 | P24941 | 1/20 | 0.72 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.72 |
| ▸ | GSK3B | P49841 | 1/20 | 0.72 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903924 | 0.86 | MAPT (0.60) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL4094794 | 0.84 | RPS6KB1 (1.00) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL5165684 | 0.84 | MAPT (0.67) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL4094953 | 0.82 | RPS6KB1 (0.50) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL11924594 | 0.81 | MAPT (0.52) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL14222025 | 0.81 | ACACB (0.59) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL4091140 | 0.80 | RPS6KB1 (0.49) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL4086750 | 0.80 | CNR2 (0.53) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL3498457 | 0.80 | ABCC1 (0.57) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL4084437 | 0.80 | RPS6KB1 (0.47) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | RPS6KB1 780/4885CDK2 645/4885MAPKAPK2 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.