Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 1.00 |
| ▸ | CDK2 | P24941 | 1/20 | 1.00 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 1.00 |
| ▸ | GSK3B | P49841 | 1/20 | 1.00 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089737 | 0.84 | RPS6KB1 (0.72) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL3767865 | 0.74 | MAPK1 (0.66) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL24455393 | 0.71 | RPS6KB1 (0.55) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL12903924 | 0.70 | MAPT (0.60) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL2162614 | 0.70 | RPS6KB1 (0.54) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL3748506 | 0.70 | RPS6KB1 (0.54) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL4723975 | 0.70 | KDM4E (0.73) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL717339 | 0.70 | ALDH1A1 (0.53) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL1218547 | 0.69 | KDM4E (0.52) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL30555073 | 0.69 | KDM4E (0.52) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | RPS6KB1 780/4885CDK2 645/4885MAPKAPK2 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.