SCHEMBL408980

SCHEMBL408980

C=COc1ccc(C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
KIF11 P52732 3/20 0.40
TGM2 P21980 1/20 0.40
MAOB P27338 4/20 0.40
AOC3 Q16853 1/20 0.40
TEAD1 P28347 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
PTGS1 P23219 1/20 0.38
IDO1 P14902 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14289127 0.83 ESR1 (0.45)
SCHEMBL473606 0.80 CHRNB2 (0.34) CA1CA2CA9ALDH1A1TSHR
SCHEMBL13374679 0.79 NR1H2 (0.51)
SCHEMBL1023907 0.77 HPGD (0.41) CA1CA2CA9ALDH1A1TSHR
SCHEMBL755402 0.77 ESR1 (0.35) CA1CA2CA9ALDH1A1
SCHEMBL3786415 0.77 MAPT (0.47) CA1CA2CA9KIF11MAOB
SCHEMBL7658787 0.77 MAPT (0.42) KIF11MAOBAOC3TEAD1ALDH1A1
SCHEMBL535428 0.77 CA1 (0.44) CA1CA2CA9KIF11MAOB
SCHEMBL513897 0.77 CA1 (0.48) CA1CA2CA9KIF11MAOB
SCHEMBL17515582 0.74 MAPT (0.33) KIF11ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722199-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2026-04-08 EP disclosed
WO-2024247919-A1 AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF 四国化成工業株式会社 2024-12-05 WO disclosed
CN-118541350-A Naphthalene compound, method for synthesizing the same, and composition containing the same 四国化成工业株式会社 2024-08-23 CN disclosed
WO-2023058781-A2 NAPHTHALENE COMPOUND, SYNTHESIS METHOD THEREFOR, AND COMPOSITION CONTAINING SAID NAPHTHALENE COMPOUND 四国化成工業株式会社 2023-04-13 WO disclosed
CN-107849167-B Method for producing polymer for electronic material and polymer for electronic material obtained by the production method 丸善石油化学株式会社 2021-02-23 CN disclosed
US-10766973-B2 Method for producing polymer for electronic material and polymer for electronic material obtained by the production method MARUZEN PETROCHEMICAL CO., LTD. (JP) 2020-09-08 US disclosed
US-20190002604-A1 HETERORING-CONTAINING SILOXANE POLYMER, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT DAINIPPON INK & CHEMICALS (JP) 2019-01-03 US disclosed
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT DAINIPPON INK & CHEMICALS (JP) 2018-08-09 US disclosed
US-20180134819-A1 METHOD FOR PRODUCING POLYMER FOR ELECTRONIC MATERIAL AND POLYMER FOR ELECTRONIC MATERIAL OBTAINED BY THE PRODUCTION METHOD MARUZEN PETROCHEMICAL CO., LTD. (JP) 2018-05-17 US disclosed
CN-107849167-A Method for producing polymer for electronic material and polymer for electronic material obtained by the production method 丸善石油化学株式会社 2018-03-27 CN disclosed
US-8492483-B2 ABA triblock copolymer and process for producing the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20120235148-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-20 US disclosed
EP-2479791-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120172535-A1 VINYL ETHER-BASED STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF MARUZEN PETROCHEMICAL CO., LTD. (JP) 2012-07-05 US disclosed
EP-2465885-A1 VINYL ETHER-BASED STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF Maruzen Petrochemical Co., Ltd. (JP) 2012-06-20 EP disclosed
US-20120053287-A1 RESIN COMPOSITION FOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LTD (JP) 2012-03-01 US disclosed
EP-2412737-A1 VINYL ETHER-BASED STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF Maruzen Petrochemical CO., LTD. (JP) 2012-02-01 EP disclosed
US-20120022219-A1 VINYL ETHER-BASED STAR POLYMER AND PROCESS FOR PRODUCTION THEREOF MARUZEN PETROCHEMICAL CO., LTD 2012-01-26 US disclosed
US-20100286351-A1 ABA TRIBLOCK COPOLYMER AND PROCESS FOR PRODUCING THE SAME MARUZEN PETROCHEMICAL CO., LTD. (JP) 2010-11-11 US disclosed
EP-2186837-A1 ABA TRIBLOCK COPOLYMER AND PROCESS FOR PRODUCING THE SAME MARUZEN PETROCHEMICAL CO., LTD. (JP) 2010-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT ILK, LIMA1, EED CA1 2560/4885CA2 3907/4885CA9 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.