Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161939 | 0.88 | TACR1 (0.43) | TACR1 | |
| Hydrochloric Acid SCHEMBL9025807 | 0.80 | TACR1 (0.44) | TACR1 | |
| SCHEMBL9042626 | 0.77 | TACR1 (0.44) | TACR1 | |
| Hydrochloric Acid SCHEMBL8542728 | 0.75 | TACR1 (0.54) | TACR1 | |
| SCHEMBL27908231 | 0.73 | CHRNB2 (0.49) | — | |
| SCHEMBL21836003 | 0.72 | CHRNB2 (0.40) | TSHRSMN1; SMN2 | |
| SCHEMBL9024202 | 0.72 | TACR1 (0.43) | TACR1 | |
| SCHEMBL9370843 | 0.71 | TACR1 (0.46) | TACR1 | |
| SCHEMBL7530795 | 0.71 | CHRNB2 (0.42) | CYP2D6CYP2C19NPSR1 | |
| Hydrochloric Acid SCHEMBL9076466 | 0.70 | TACR1 (0.49) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079301-A1 | IMPROVED TISSUE MAINTENANCE | Hibernation Therapeutics Limited (AU) | 2009-07-22 | — | — | EP | disclosed |
| WO-2007137321-A1 | IMPROVED TISSUE MAINTENANCE | HIBERNATION THERAPEUTICS LIMITED (AU) | 2007-12-06 | — | — | WO | disclosed |