Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22598707 | 0.82 | PSMB8 (0.41) | MEN1HPGDKMT2AHSD17B10ADORA2A | |
| SCHEMBL26956220 | 0.80 | ALDH1A1 (0.48) | MEN1HPGDKMT2AHSD17B10ADORA2A | |
| SCHEMBL18762215 | 0.80 | MEN1 (0.41) | MEN1HPGDKMT2AHSD17B10ADORA2A | |
| SCHEMBL31698451 | 0.76 | ESR1 (0.41) | MEN1HPGDKMT2AHSD17B10ADORA2A | |
| SCHEMBL9981015 | 0.76 | DPP4 (0.41) | MEN1KMT2AFGFR1PRPS1RAB9A | |
| SCHEMBL7027324 | 0.72 | ADORA2A (0.42) | MEN1HPGDKMT2AHSD17B10ADORA2A | |
| SCHEMBL1027011 | 0.69 | HPGD (0.68) | MEN1HPGDKMT2AHSD17B10HCAR3 | |
| SCHEMBL31390868 | 0.68 | HCAR3 (0.57) | HPGDADORA2AADORA1ABL1HCAR3 | |
| Hydrochloric Acid SCHEMBL9787788 | 0.68 | HPGD (0.66) | MEN1HPGDKMT2AHSD17B10HCAR3 | |
| Bromide SCHEMBL10432863 | 0.68 | HPGD (0.66) | MEN1HPGDKMT2AHSD17B10HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |