Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076372 | 0.88 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CGMAPTSMN1; SMN2 | |
| SCHEMBL4484753 | 0.84 | MAPT (0.40) | MAPTSMN1; SMN2TP53ALOX5KDM4E | |
| SCHEMBL3971582 | 0.78 | MAPT (0.35) | MAPTSMN1; SMN2TP53ALOX5KDM4E | |
| SCHEMBL4073483 | 0.77 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGMAPTSMN1; SMN2 | |
| SCHEMBL4075677 | 0.74 | MAPT (0.41) | MAPTSMN1; SMN2TP53ALOX5KDM4E | |
| SCHEMBL3170904 | 0.60 | KMT2A (0.52) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL3166865 | 0.55 | MAOA (0.54) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL4086084 | 0.54 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CGMAPTALOX5 | |
| SCHEMBL12063336 | 0.53 | MIF (0.52) | — | |
| SCHEMBL4116817 | 0.53 | MAP3K14 (0.48) | PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |