Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484753 | 0.89 | MAPT (0.40) | MAPTSMN1; SMN2TP53LMNAALOX5 | |
| SCHEMBL4090064 | 0.78 | PIK3CD (0.34) | MAPTSMN1; SMN2TP53LMNAALOX5 | |
| SCHEMBL4075677 | 0.78 | MAPT (0.41) | MAPTSMN1; SMN2TP53LMNAALOX5 | |
| SCHEMBL2718592 | 0.72 | CYP19A1 (0.39) | — | |
| Bromide SCHEMBL3979336 | 0.71 | CYP19A1 (0.39) | — | |
| SCHEMBL9096104 | 0.63 | HTR2A (0.39) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4076372 | 0.61 | PIK3CD (0.37) | MAPTSMN1; SMN2TP53KMT2AALDH1A1 | |
| SCHEMBL23792237 | 0.61 | CYP11B2 (0.47) | — | |
| SCHEMBL2730840 | 0.60 | HTR2A (0.47) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4073483 | 0.59 | PIK3CD (0.46) | MAPTSMN1; SMN2TP53LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |