Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | AIP | O00170 | 1/20 | 0.36 |
| ▸ | SGTA | O43765 | 1/20 | 0.36 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.36 |
| ▸ | STIP1 | P31948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094731 | 0.93 | KMT2A (0.39) | ABCC1KIF11RPS6KB1CDK2MAPKAPK2 | |
| SCHEMBL4091042 | 0.90 | ABCC1 (0.44) | ABCC1KIF11RPS6KB1CDK2MAPKAPK2 | |
| SCHEMBL4084751 | 0.77 | CNR2 (0.58) | ABCC1RPS6KB1CDK2MAPKAPK2GSK3B | |
| SCHEMBL3745498 | 0.77 | ABCC1 (0.51) | ABCC1RPS6KB1CDK2MAPKAPK2GSK3B | |
| SCHEMBL4080989 | 0.76 | CNR2 (0.46) | ABCC1RPS6KB1CDK2MAPKAPK2GSK3B | |
| SCHEMBL3767865 | 0.76 | MAPK1 (0.66) | RPS6KB1CDK2MAPKAPK2GSK3BRPS6KA3 | |
| SCHEMBL4091316 | 0.76 | ALDH1A1 (0.58) | KMT2AMAPK1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4092577 | 0.75 | CNR2 (0.51) | ABCC1RPS6KB1CDK2MAPKAPK2GSK3B | |
| SCHEMBL4080504 | 0.74 | CNR2 (0.50) | ABCC1RPS6KB1CDK2MAPKAPK2GSK3B | |
| SCHEMBL4090409 | 0.73 | ALDH1A1 (0.44) | ABCC1KIF11RPS6KB1CDK2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | ABCC1 2675/4885KIF11 4210/4885RPS6KB1 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.