Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CETP | P11597 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347743 | 0.86 | CA12 (0.55) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL347742 | 0.86 | CA12 (0.55) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL4087652 | 0.84 | CA12 (0.56) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL4087650 | 0.84 | CA12 (0.56) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL347930 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL4093773 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL4085482 | 0.80 | AR (0.65) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL4080666 | 0.80 | KMT2A (0.51) | ALDH1A1CETPKMT2ANPSR1HTT | |
| SCHEMBL7062983 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KMT2AHTTLMNAMAPT | |
| SCHEMBL347552 | 0.79 | PTGDR2 (0.62) | ALDH1A1CETPKMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221604-A1 | Thiazole Compounds and Their Use as PGD2 Antagonists | ARGENTA DISCOVERY LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-1922312-A1 | THIAZOLE COMPOUNDS AND THEIR USE AS PGD2 ANTAGONISTS | Argenta Discovery Limited (GB) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007028999-A1 | THIAZOLE COMPOUNDS AND THEIR USE AS PGD2 ANTAGONISTS | ARGENTA DISCOVERY LIMITED (GB) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221604-A1 | Thiazole Compounds and Their Use as PGD2 Antagonists | PTGDR2, PTGDR, PTGER2 | ALDH1A1 3327/4885CETP 4678/4885KMT2A 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.