Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | AR | P10275 | 3/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484530 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ARALOX5LMNAMEN1 | |
| SCHEMBL8056967 | 0.80 | AR (0.72) | ALDH1A1ARALOX5LMNAMAPT | |
| SCHEMBL4091068 | 0.79 | ALDH1A1 (0.65) | ALDH1A1ARLMNAKMT2AMAPT | |
| SCHEMBL17009411 | 0.79 | AR (1.00) | ALDH1A1ARALOX5LMNAMAPT | |
| SCHEMBL8419989 | 0.78 | AR (0.65) | ALDH1A1ARALOX5LMNAMEN1 | |
| SCHEMBL8823050 | 0.78 | ALDH1A1 (0.79) | ALDH1A1ARALOX5LMNAHTT | |
| SCHEMBL17014756 | 0.76 | AR (1.00) | ALDH1A1ARALOX5LMNAMAPT | |
| SCHEMBL10288312 | 0.74 | ALDH1A1 (0.59) | ALDH1A1ARALOX5LMNAMAPT | |
| SCHEMBL2559774 | 0.74 | ALDH1A1 (0.58) | ALDH1A1ARMEN1KMT2AMAPT | |
| SCHEMBL25932800 | 0.74 | ALDH1A1 (0.71) | ALDH1A1ARMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183319-A1 | HUMAN ANDROGEN RECEPTOR DNA-BINDING DOMAN (DBD) COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-06-29 | — | — | US | disclosed |
| WO-2015120543-A1 | HUMAN ANDROGEN RECEPTOR DNA-BINDING DOMAIN (DBD) COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-08-20 | — | — | WO | disclosed |
| EP-1312986-A1 | Magenta-colored toner particles for electrostatographic imaging | NexPress Solutions LLC (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6528223-B1 | Particle composition comprising binder polymer and specified dye having various substituents introduced into aromatic ring at thiazolyl 4-position, to avoid tendency toward dye crystallization | NEXPRESS SOLUTIONS LLC | 2003-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183319-A1 | HUMAN ANDROGEN RECEPTOR DNA-BINDING DOMAN (DBD) COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | AR, FSHR, ESRRB | ALDH1A1 2525/4885AR 1/4885ALOX5 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.