Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13940749 | 0.71 | IDO1 (0.47) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL358102 | 0.70 | NR1H2 (0.45) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4091146 | 0.70 | IDO1 (0.50) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL8002346 | 0.66 | HPGD (0.50) | KDM4EKMT2AHPGDHTTALDH1A1 | |
| SCHEMBL10259123 | 0.65 | HPGD (0.49) | KDM4EHPGDHTTALDH1A1LMNA | |
| SCHEMBL17517333 | 0.65 | ALDH1A1 (0.41) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL23029789 | 0.64 | IDO1 (0.48) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL8977944 | 0.64 | PDE4A (0.43) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL17522143 | 0.63 | TSHR (0.52) | KDM4EKMT2AHPGDHTTALDH1A1 | |
| SCHEMBL20661372 | 0.63 | ALDH1A1 (0.49) | KDM4EMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018128-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2009-01-15 | — | — | US | disclosed |
| EP-1979358-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088168-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018128-A1 | Compounds | CNR2, CNR1, TRPV1 | KDM4E 2515/4885MEN1 4367/4885KMT2A 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.