Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960054 | 0.82 | ALDH1A1 (0.47) | PDE4ANUDT1CYP1A2CYP3A4GABRA1 | |
| SCHEMBL17781174 | 0.73 | PDE4A (0.48) | PDE4ANUDT1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL26134669 | 0.72 | ALDH1A1 (0.41) | GABRA1GABRB2KDM4EALDH1A1HPGD | |
| SCHEMBL31364057 | 0.71 | PDE4A (0.41) | PDE4AGABRA1GABRB2LMNAALDH1A1 | |
| SCHEMBL1695429 | 0.71 | RAB9A (0.50) | PDE4ALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL343502 | 0.71 | GAA (0.59) | CYP1A2LMNACYP2C19KDM4EALDH1A1 | |
| SCHEMBL30520974 | 0.71 | PDE4A (0.52) | PDE4ACYP1A2KDM4EALDH1A1RAB9A | |
| SCHEMBL9920381 | 0.70 | ALDH1A1 (0.46) | PDE4ACYP1A2CYP3A4LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL28348022 | 0.70 | GAA (0.58) | CYP1A2LMNACYP2C19KDM4EALDH1A1 | |
| SCHEMBL1431721 | 0.70 | RAB9A (0.50) | PDE4ACYP1A2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525480-A | USED FOR DETERMINATION OF HYDROLASES; COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5457200-A | Oxidative coupling reactions for determination of hydrogen peroxide | BOEHRINGER MANNHEIM (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| US-5234818-A | Detecting hydrogen peroxide, peroxidase by oxidative coupling with electron-rich aromatic compound | BOEHRINGER MANNHEIM GMBH (DE) | 1993-08-10 | — | — | US | disclosed |