SCHEMBL409138

SCHEMBL409138

CCCCCCCCCCCCOCC(O)C[N+](CCC)(CCC)CCCOP(=O)(O)O

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 5/20 0.64
LPAR3 Q9UBY5 12/20 0.54
LPAR1 Q92633 10/20 0.54
LPAR2 Q9HBW0 8/20 0.54
USP2 O75604 1/20 0.47
HTT P42858 1/20 0.46
P2RY10 O00398 1/20 0.45
PLA2G2C Q5R387 2/20 0.41
LPAR6 P43657 4/20 0.41
LPAR4 Q99677 4/20 0.41
ENPP2 Q13822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL9053410 0.89 LPAR5 (0.61) LPAR5LPAR3LPAR1LPAR2USP2
Phosphoric Acid SCHEMBL409139 0.87 LPAR5 (0.58) LPAR5LPAR3LPAR1USP2HTT
SCHEMBL80315 0.86 LPAR5 (0.55) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL1445519 0.85 USP2 (0.62) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL2454903 0.84 LPAR5 (0.52) LPAR5LPAR3LPAR1USP2HTT
SCHEMBL6234843 0.82 LPAR5 (0.68) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL6236700 0.82 LPAR5 (0.68) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL6235250 0.82 LPAR5 (0.68) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL9837881 0.82 LPAR5 (0.68) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL7829804 0.79 LPAR5 (1.00) LPAR5LPAR3LPAR1LPAR2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395235-B1 SHAMPOOS WITH BEHENYL ALCOHOL COLGATE PALMOLIVE CO (US) 2007-02-28 EP claimed
US-11110175-B2 Compositions with permeation enhancers for drug delivery CHILDREN'S MEDICAL CENTER CORPORATION (US) 2021-09-07 US disclosed
US-20200138710-A1 COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY CHILDREN'S MEDICAL CENTER CORPORATION (US) 2020-05-07 US disclosed
EP-3512501-A1 COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY Children's Medical Center Corporation (US) 2019-07-24 EP disclosed
EP-3331547-A1 COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY Children's Medical Center Corporation (US) 2018-06-13 EP disclosed
WO-2018053140-A1 COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY CHILDREN'S MEDICAL CENTER CORPORATION (US) 2018-03-22 WO disclosed
WO-2017024282-A1 COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY CHILDREN'S MEDICAL CENTER CORPORATION (US) 2017-02-09 WO disclosed
US-20150104645-A1 MAGNETIC NANOFLAKES GABAY ALEXANDR (US) 2015-04-16 US disclosed
US-8822410-B2 Tympanic membrane permeating ear drops and uses thereof CHILDREN'S MEDICAL CENTER CORPORATION (US) 2014-09-02 US disclosed
US-20120021219-A1 MAGNETIC NANOFLAKES ELECTRON ENERGY CORPORATION 2012-01-26 US disclosed
EP-0831762-A4 ORAL CARE ULTRAMULSION BASED PRODUCTS WHITEHILL ORAL TECH INC (US) 1999-08-11 EP disclosed
EP-0831762-A1 ORAL CARE ULTRAMULSION BASED PRODUCTS WHITEHILL ORAL TECHNOLOGIES INC. (US) 1998-04-01 EP disclosed
EP-0600032-B1 HAIR SPRAY COMPOSITIONS PROCTER & GAMBLE (US) 1997-11-26 EP disclosed
US-5665374-A Ultramulsion containing interdental delivery devices WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1997-09-09 US disclosed
US-5651959-A SILICONE DISPERSION IN SURFACTANTS WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1997-07-29 US disclosed
EP-0525078-B1 ANTI-LICE TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 1997-07-23 EP disclosed
US-5645841-A Ultramulsion based oral care rinse compositions WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1997-07-08 US disclosed
WO-1996039249-A1 ULTRAMULSION BASED PAINT AND COATING PRODUCTS WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1996-12-12 WO disclosed
WO-1996039116-A1 ORAL CARE ULTRAMULSION BASED PRODUCTS WHITEHILL ORAL TECHNOLOGIES, INC. (US) 1996-12-12 WO disclosed
US-5292504-A Pyrethrins THE PROCTER & GAMBLE COMPANY (US) 1994-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11110175-B2 Compositions with permeation enhancers for drug delivery ABCB11, MMP1, SLC47A1 LPAR5 1588/4885LPAR3 2575/4885LPAR1 2379/4885
US-20200138710-A1 COMPOSITIONS WITH PERMEATION ENHANCERS FOR DRUG DELIVERY ABCB11, CFTR, MMP1 LPAR5 1841/4885LPAR3 2926/4885LPAR1 2448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.