Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086500 | 0.78 | KMT2A (0.44) | L3MBTL1KMT2AOPRM1OPRK1KCNH2 | |
| SCHEMBL4086487 | 0.73 | HDAC8 (0.58) | HDAC8KMT2ALMNAKCNH2 | |
| SCHEMBL19364501 | 0.73 | CHRM2 (0.53) | L3MBTL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL707808 | 0.73 | CHRM2 (0.53) | L3MBTL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL16766368 | 0.73 | CHRM2 (0.53) | L3MBTL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL719296 | 0.73 | CHRM2 (0.53) | L3MBTL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL29691892 | 0.73 | CHRM2 (0.53) | L3MBTL1OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL13604588 | 0.73 | CHRM2 (0.53) | KMT2AMEN1OPRM1OPRK1KCNH2 | |
| SCHEMBL3903429 | 0.73 | CHRM2 (0.53) | KMT2AMEN1OPRM1OPRK1KCNH2 | |
| SCHEMBL20483452 | 0.72 | CHRM2 (0.64) | KMT2ALTA4HMEN1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117808-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-10-01 | — | — | WO | claimed |
| WO-2009117808-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009117808-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-10-01 | — | — | WO | disclosed |