Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922424 | 0.89 | KMT2A (0.42) | KMT2AL3MBTL1ESR2OPRK1 | |
| SCHEMBL30686540 | 0.82 | HTR2C (0.51) | ESR2 | |
| SCHEMBL4091940 | 0.78 | HDAC8 (0.48) | KMT2AL3MBTL1OPRK1KCNH2OPRM1 | |
| SCHEMBL5690573 | 0.78 | L3MBTL1 (0.50) | KMT2AL3MBTL1ESR2 | |
| SCHEMBL17317915 | 0.77 | ESR2 (0.44) | KMT2AL3MBTL1ESR2 | |
| SCHEMBL7326311 | 0.77 | ESR2 (0.46) | ESR2OPRM1 | |
| SCHEMBL7326318 | 0.77 | ESR2 (0.46) | ESR2OPRM1 | |
| SCHEMBL7326329 | 0.77 | ESR2 (0.46) | ESR2OPRM1 | |
| SCHEMBL4579407 | 0.75 | KMT2A (0.56) | KMT2AESR2 | |
| SCHEMBL14127784 | 0.75 | ESR2 (0.46) | KMT2AL3MBTL1ESR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117808-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009117808-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-10-01 | — | — | WO | disclosed |
| US-5561149-A | FOR NASAL ADMINISTRATION | SANDOZ LTD. (CH) | 1996-10-01 | — | — | US | disclosed |
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |