SCHEMBL4091956

SCHEMBL4091956

Clc1cc(Cl)cc([C](c2cc(Cl)cc(Cl)c2)c2cc(Cl)cc(Cl)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
TPMT P51580 1/20 0.55
CYP3A4 P08684 2/20 0.42
TP53 P04637 1/20 0.42
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
HCAR1 Q9BXC0 1/20 0.40
RECQL P46063 1/20 0.40
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
RXRA P19793 2/20 0.37
RXRB P28702 2/20 0.37
RAB9A P51151 1/20 0.37
HPGD P15428 1/20 0.35
FLT1 P17948 1/20 0.34
FLT4 P35916 1/20 0.34
KDR P35968 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL349819 0.76 TPMT (0.59) TSHRTPMTALDH1A1HCAR1RXRA
1,3,5-Trichlorobenzene SCHEMBL429512 0.76
SCHEMBL4465360 0.73 TPMT (0.65) TSHRTPMTHCAR1RXRARXRB
SCHEMBL16956186 0.73 TSHR (0.50) TSHRTPMTCYP3A4TP53ALDH1A1
SCHEMBL3073672 0.73 TSHR (0.50) TSHRTPMTCYP3A4TP53ALDH1A1
SCHEMBL2170895 0.71 TPMT (0.62) TSHRTPMTHCAR1RXRARXRB
SCHEMBL16959382 0.71 TPMT (0.55) TSHRTPMTCYP3A4TP53ALDH1A1
SCHEMBL93282 0.71 TPMT (0.62) TSHRTPMTHSD17B10HCAR1HTR3E
SCHEMBL19998298 0.71 TPMT (0.62) TSHRTPMTHCAR1RXRARXRB
SCHEMBL9586261 0.71 TPMT (0.55) TSHRTPMTCYP3A4TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2048168-A2 Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048167-A2 First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048170-A2 Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048169-A2 Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
US-6914108-B2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-05 US disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed