Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465360 | 0.77 | TPMT (0.65) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL7495444 | 0.76 | HPGD (0.43) | TPMTTSHRRAB9ATTRMEN1 | |
| SCHEMBL4091956 | 0.76 | TSHR (0.57) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL2486695 | 0.75 | PARP1 (0.63) | RAB9AFLT1FLT4KDRPARP1 | |
| SCHEMBL28214359 | 0.74 | TPMT (1.00) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL19998298 | 0.74 | TPMT (0.62) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL93282 | 0.74 | TPMT (0.62) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL2170895 | 0.74 | TPMT (0.62) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL69625 | 0.74 | TPMT (0.89) | TPMTHCAR1TSHRRXRARXRB | |
| SCHEMBL23699 | 0.74 | TPMT (1.00) | TPMTHCAR1TSHRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058553-A1 | Novel bicyclic hydroxamates as inhibitors of histone deacetylase | AXYS PHARMACEUTICALS, INC. (US) | 2006-03-16 | — | — | US | claimed |
| EP-1472216-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | Axys Pharmaceuticals (US) | 2004-11-03 | — | — | EP | claimed |
| WO-2003066579-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | AXYS PHARMACEUTICALS (US) | 2003-08-14 | — | — | WO | claimed |
| US-20030055096-A1 | Fungicidal composition | OGURI YUKIO (JP) | 2003-03-20 | — | — | US | claimed |
| EP-0741970-B1 | BACTERICIDAL COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 2002-04-24 | — | — | EP | claimed |
| EP-0793914-B1 | Fungicidal Composition | SUMITOMO CHEMICAL CO (JP) | 1999-09-15 | — | — | EP | claimed |
| EP-0793914-A1 | Microbicidal Composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-09-10 | — | — | EP | claimed |
| EP-0741970-A1 | BACTERICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-11-13 | — | — | EP | claimed |
| EP-0096307-B1 | FUNGICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-01-07 | — | — | EP | claimed |
| EP-0096307-A1 | Fungicidal composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-12-21 | — | — | EP | claimed |
| JP-61063607-A | — | — | None | — | — | JP | disclosed |
| JP-9241110-A | — | — | None | — | — | JP | disclosed |
| JP-58208201-A | — | — | None | — | — | JP | disclosed |
| JP-63002907-A | — | — | None | — | — | JP | disclosed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| JP-S6163607-A | AGRICULTURAL AND HORTICULTURAL FUNGICIDAL COMPOSITION | SUMITOMO CHEM CO LTD | 1986-04-01 | — | — | JP | disclosed |
| EP-0096307-A1 | Fungicidal composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-12-21 | — | — | EP | disclosed |
| EP-0096307-A1 | Fungicidal composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-12-21 | — | — | EP | disclosed |
| JP-S58208201-A | AGRICULTURAL AND HORTICULTURAL GERMICIDAL COMPOSITION | SUMITOMO CHEM CO LTD | 1983-12-03 | — | — | JP | disclosed |
| US-4009278-A | Antimicrobial composition and method containing N-(3,5-dihalophenyl)-imide compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055096-A1 | Fungicidal composition | CBR1, CBR3, CYP1B1 | TPMT 1243/4885HCAR1 2740/4885TSHR 1948/4885 |
| US-20060058553-A1 | Novel bicyclic hydroxamates as inhibitors of histone deacetylase | HDAC1, HDAC2, HDAC11 | TPMT 2626/4885HCAR1 157/4885TSHR 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.