SCHEMBL4092055

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14642069	0.91	HSP90AA1 (0.46)	HSP90AA1RAB9ASMN1; SMN2NPC1ADORA2A
	SCHEMBL4086112	0.88	HSP90AA1 (0.43)	HSP90AA1RAB9ASMN1; SMN2NPC1ADORA2A
	SCHEMBL2847985	0.82	HSP90AA1 (0.50)	HSP90AA1RAB9ASMN1; SMN2NPC1ADORA2A
	SCHEMBL4091773	0.79	HSP90AA1 (0.52)	HSP90AA1RAB9ASMN1; SMN2NPC1BACE1
	SCHEMBL4093400	0.78	HSP90AA1 (0.46)	HSP90AA1RAB9ASMN1; SMN2NPC1ADORA2A
	SCHEMBL4086244	0.77	TP53 (0.48)	HSP90AA1RAB9ASMN1; SMN2NPC1ADORA2A
	SCHEMBL3943328	0.75	HSP90AA1 (0.60)	HSP90AA1BACE1MGAMGAASI
	SCHEMBL4086685	0.73	HSP90AB1 (0.41)	HSP90AA1ADORA2AADORA1ADORA3
	SCHEMBL4085660	0.73	CA12 (0.49)	HSP90AA1RAB9ASMN1; SMN2NPC1PAK4
	SCHEMBL4098596	0.72	CXCR2 (0.41)	HSP90AA1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.