Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.81 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 11/20 | 0.42 |
| ▸ | PPARA | Q07869 | 9/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP4X1 | Q8N118 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093589 | 0.89 | PTGES (1.00) | PTGESTRPV1PPARGPPARASERPINE1 | |
| SCHEMBL4086539 | 0.88 | PTGES (0.62) | PTGESTP53SERPINE1KMT2ASMN1; SMN2 | |
| SCHEMBL15497056 | 0.77 | PTGES (0.48) | PTGESTRPV1PPARGPPARATP53 | |
| SCHEMBL4092414 | 0.75 | PTGES (0.72) | PTGESSERPINE1CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL4086709 | 0.74 | PTGES (0.47) | PTGESPPARGTP53KMT2ASMN1; SMN2 | |
| SCHEMBL4098784 | 0.72 | TP53 (0.46) | PTGESTP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4086421 | 0.71 | MAPT (0.48) | PTGESTP53KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5812761 | 0.71 | PTGES (0.65) | PTGESPPARGPPARASERPINE1PLA2G2A | |
| SCHEMBL15497062 | 0.71 | KMT2A (0.46) | PTGESTP53ALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL5737792 | 0.69 | PPARG (0.46) | PTGESPPARGPPARASERPINE1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
| EP-1844051-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077412-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | PTGES 3/4885TRPV1 866/4885PPARG 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.