Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.72 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.50 |
| ▸ | CCR9 | P51686 | 10/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086539 | 0.88 | PTGES (0.62) | PTGESSERPINE1CCR9PLA2G2AALDH1A1 | |
| SCHEMBL4093589 | 0.84 | PTGES (1.00) | PTGESSERPINE1CCR2ERCC5CYP2C9 | |
| SCHEMBL6089872 | 0.78 | SERPINE1 (0.59) | PTGESSERPINE1CCR9PLA2G2AEDNRB | |
| SCHEMBL5738857 | 0.78 | SERPINE1 (0.56) | PTGESSERPINE1CCR9PLA2G2AEDNRB | |
| SCHEMBL5812761 | 0.76 | PTGES (0.65) | PTGESSERPINE1PLA2G2AEDNRBEDNRA | |
| SCHEMBL4092264 | 0.75 | PTGES (0.81) | PTGESSERPINE1PLA2G2ACYP1A2CYP2D6 | |
| SCHEMBL4096957 | 0.72 | PTGES (0.52) | PTGESCCR2ERCC5PLA2G2AMAPT | |
| SCHEMBL6091652 | 0.72 | SERPINE1 (0.54) | PTGESSERPINE1CCR9PLA2G2A | |
| SCHEMBL6093040 | 0.72 | SERPINE1 (0.45) | PTGESSERPINE1CCR9PLA2G2A | |
| SCHEMBL15497058 | 0.71 | PTGES (0.55) | PTGESCCR9CCR2ERCC5PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069384-A1 | THIENOPYRROLES USEFUL IN THE TREATMENT OF INFLAMMATION | NPY5R, TH, PTGES | PTGES 3/4885SERPINE1 1731/4885CCR9 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.