SCHEMBL4092523

CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@H](C(=O)OC)C(C)C.CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)[C@H](C(=O)OC)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	AGTR1	P30556	14/20	0.59

▸	LTB4R2	Q9NPC1	5/20	0.50

▸	ABCB11	O95342	1/20	0.50

▸	GP6	Q9HCN6	1/20	0.50

▸	AGT	P01019	2/20	0.40

▸	AGTR2	P50052	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2443650	0.93	AGTR1 (0.63)	AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL1259493	0.93	AGTR1 (0.63)	AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL29670077	0.93	AGTR1 (0.63)	AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL8140438	0.89	AGTR1 (0.56)	AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL2373	0.89	AGTR1 (0.73)	AGTR1LTB4R2ABCB11GP6
SCHEMBL2251	0.89	AGTR1 (0.73)	AGTR1LTB4R2ABCB11GP6
SCHEMBL29669823	0.89	AGTR1 (0.73)	AGTR1LTB4R2ABCB11GP6
SCHEMBL2252	0.89	AGTR1 (0.73)	AGTR1LTB4R2ABCB11GP6
SCHEMBL29205124	0.87	AGTR1 (0.54)	AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL29205122	0.87	AGTR1 (0.54)	AGTR1LTB4R2ABCB11GP6AGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2057132-A2	PROCESS FOR THE PREPARATION OF THE ANGIOTENSIN II ANTAGONIST VALSARTAN	Aurobindo Pharma Limited (IN)	2009-05-13	—	—	EP	disclosed
WO-2008004110-A2	PROCESS FOR THE PREPARATION OF THE ANGIOTENSIN II ANTAGONIST VALSARTAN	AUROBINDO PHARMA LIMITED (IN)	2008-01-10	—	—	WO	disclosed