Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGFR | P43088 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL4355557 | 0.98 | TEAD4 (0.54) | TEAD4CYP1A2CYP2A6ALOX5TBXA2R | |
| SCHEMBL2838141 | 0.87 | CYP1A2 (0.65) | TEAD4CYP1A2CYP2A6ALOX5CTRC | |
| Sulfuric Acid SCHEMBL6378742 | 0.86 | TEAD4 (0.54) | TEAD4CYP1A2CYP2A6ALOX5CTRC | |
| SCHEMBL5900962 | 0.82 | CYP1A2 (0.60) | TEAD4CYP1A2CYP2A6ALOX5CTRC | |
| SCHEMBL28846677 | 0.82 | CYP1A2 (0.60) | TEAD4CYP1A2CYP2A6ALOX5CTRC | |
| Menaphthyl Sulfonate SCHEMBL294032 | 0.82 | CYP1A2 (0.50) | TEAD4CYP1A2CYP2A6NPY1RNPY5R | |
| SCHEMBL598561 | 0.80 | CYP1A2 (0.58) | TEAD4CYP1A2CYP2A6ALOX5TBXA2R | |
| SCHEMBL29417927 | 0.80 | CYP1A2 (0.58) | TEAD4CYP1A2CYP2A6ALOX5TBXA2R | |
| Menaphthyl Sulfonate SCHEMBL6980474 | 0.80 | CYP1A2 (0.48) | TEAD4CYP1A2CYP2A6NPY1RNPY5R | |
| SCHEMBL29001425 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214648-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING IBUPROFEN AND DIPHENHYDRAMINE | DR. REDDY'S LABORATORIES, INC. | 2009-08-27 | — | — | US | claimed |
| US-5393461-A | For use in cosmetics, paints, drugs,inks; mixing powder with anionic, cationic, amphoteric, nonionic surfactants, oils, solvents, wetting agents and water, emulsification | RTD CORPORATION (US) | 1995-02-28 | — | — | US | claimed |
| US-20240082117-A1 | Method of Dispersing Hydrophobic Substances in Aqueous Cleansing System | RENMATIX INC (US) | 2024-03-14 | — | — | US | disclosed |
| US-20090214648-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING IBUPROFEN AND DIPHENHYDRAMINE | DR. REDDY'S LABORATORIES, INC. | 2009-08-27 | — | — | US | disclosed |
| US-5393461-A | For use in cosmetics, paints, drugs,inks; mixing powder with anionic, cationic, amphoteric, nonionic surfactants, oils, solvents, wetting agents and water, emulsification | RTD CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214648-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING IBUPROFEN AND DIPHENHYDRAMINE | HRH1, HRH4, HRH2 | TEAD4 1618/4885CYP1A2 97/4885CYP2A6 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.