SCHEMBL4093243

SCHEMBL4093243

CC(=O)c1cccc(S(=O)(=O)F)c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.55
LMNA P02545 3/20 0.55
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
HTT P42858 2/20 0.50
CA2 P00918 2/20 0.49
POLB P06746 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.46
ACLY P53396 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA9 Q16790 1/20 0.44
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901134 0.82 F2 (0.57) ALDH1A1LMNAKMT2ACA2CA12
SCHEMBL212547 0.82 ALDH1A1 (0.57) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL4638087 0.82 ALDH1A1 (0.57) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL1436244 0.82 F2 (0.57) ALDH1A1LMNAKMT2ACA2CA12
SCHEMBL3653439 0.81 MEN1 (0.65) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL11769980 0.81 CA2 (0.53) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL31439621 0.81 F2 (0.56) ALDH1A1LMNAKMT2ACA2CA12
SCHEMBL3347957 0.81 CA2 (0.63) ALDH1A1LMNAKMT2ASMN1; SMN2CA2
SCHEMBL11585746 0.81 ALDH1A1 (0.55) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL533063 0.81 ALDH1A1 (0.55) ALDH1A1LMNAKMT2ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1858540-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES Bio-Rad Laboratories, Inc. (US) 2007-11-28 EP claimed
WO-2006088624-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES BIO-RAD LABORATORIES, INC. (US) 2006-08-24 WO claimed
US-20060183681-A1 Stabilized compositions containing natriuretic peptides BIO-RAD LABORATORIES, INC. (US) 2006-08-17 US claimed
US-20200158739-A1 METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID QUIDEL CORPORATION 2020-05-21 US disclosed
US-10641781-B2 Method, composition and device for sampling natriuretic peptides in a biological fluid CRIMSON U.S. ASSETS LLC (US) 2020-05-05 US disclosed
US-20170003305-A1 METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID CRIMSON U.S. ASSETS LLC (US) 2017-01-05 US disclosed
US-9482677-B2 Method, composition and device for sampling natriuretic peptides in a biological fluid SCIOS INC. (US) 2016-11-01 US disclosed
EP-2098866-B1 Method, composition and device for sampling natriuretic peptides in a biological fluid SCIOS INC (US) 2013-05-01 EP disclosed
EP-2098866-A1 Method, composition and device for sampling natriuretic peptides in a biological fluid Scios Inc. (US) 2009-09-09 EP disclosed
US-20090215182-A1 METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID QUIDEL CORPORATION 2009-08-27 US disclosed
EP-1858540-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES Bio-Rad Laboratories, Inc. (US) 2007-11-28 EP disclosed
US-6037362-A CARBAZOLE DERIVATIVES; DEPROTECTING, AMINATION; ANTILIPEMIC AND ANTIDIABETIC AGENTS; B-ADRENALINE RECEPTOR AGONISTS; DIETETICS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-03-14 US disclosed
US-5973156-A Piperidine and tetrahydropyridine derivatives MERCK SHARP & DOME LTD. (GB) 1999-10-26 US disclosed
EP-0882707-A1 NOVEL TRICYCLIC COMPOUNDS AND DRUG COMPOSITIONS CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-12-09 EP disclosed
EP-0861245-A1 PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES MERCK SHARP & DOHME LTD. (GB) 1998-09-02 EP disclosed
WO-1997019073-A1 PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1997-05-29 WO disclosed
US-5459131-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1995-10-17 US disclosed
EP-0206714-B1 PROCESS FOR THE PREPARATION OF AN AMINE TERMINATED POLYBUTADIENE ELF ATOCHEM S.A. (FR) 1991-03-13 EP disclosed
EP-0206714-A1 Process for the preparation of an amine terminated polybutadiene ELF ATOCHEM S.A. (FR) 1986-12-30 EP disclosed
US-4065459-A SULFONATION PARCOR (FR) 1977-12-27 US disclosed