SCHEMBL4093243

SCHEMBL4093243

CC(=O)c1cccc(S(=O)(=O)F)c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 13/20 0.55
▸ LMNA P02545 3/20 0.55
▸ KMT2A Q03164 2/20 0.51
▸ SMN1; SMN2 Q16637 4/20 0.50
▸ HTT P42858 2/20 0.50
▸ CA2 P00918 2/20 0.49
▸ POLB P06746 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ SIRT2 Q8IXJ6 1/20 0.46
▸ ACLY P53396 1/20 0.45
▸ CA12 O43570 1/20 0.44
▸ CA1 P00915 1/20 0.44
▸ CA9 Q16790 1/20 0.44
▸ MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30901134 0.82 F2 (0.57) ALDH1A1LMNAKMT2ACA2CA12
SCHEMBL1436244 0.82 F2 (0.57) ALDH1A1LMNAKMT2ACA2CA12
SCHEMBL4638087 0.82 ALDH1A1 (0.57) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL212547 0.82 ALDH1A1 (0.57) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL3653439 0.81 MEN1 (0.65) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL11769980 0.81 CA2 (0.53) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL533063 0.81 ALDH1A1 (0.55) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL11585746 0.81 ALDH1A1 (0.55) ALDH1A1LMNAKMT2ASMN1; SMN2HTT
SCHEMBL3347957 0.81 CA2 (0.63) ALDH1A1LMNAKMT2ASMN1; SMN2CA2
SCHEMBL31439621 0.81 F2 (0.56) ALDH1A1LMNAKMT2ACA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1858540-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES Bio-Rad Laboratories, Inc. (US) 2007-11-28 — — EP claimed
WO-2006088624-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES BIO-RAD LABORATORIES, INC. (US) 2006-08-24 — — WO claimed
US-20060183681-A1 Stabilized compositions containing natriuretic peptides BIO-RAD LABORATORIES, INC. (US) 2006-08-17 — — US claimed
US-20200158739-A1 METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID QUIDEL CORPORATION 2020-05-21 — — US disclosed
US-10641781-B2 Method, composition and device for sampling natriuretic peptides in a biological fluid CRIMSON U.S. ASSETS LLC (US) 2020-05-05 — — US disclosed
US-20170003305-A1 METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID CRIMSON U.S. ASSETS LLC (US) 2017-01-05 — — US disclosed
US-9482677-B2 Method, composition and device for sampling natriuretic peptides in a biological fluid SCIOS INC. (US) 2016-11-01 — — US disclosed
EP-2098866-B1 Method, composition and device for sampling natriuretic peptides in a biological fluid SCIOS INC (US) 2013-05-01 — — EP disclosed
EP-2098866-A1 Method, composition and device for sampling natriuretic peptides in a biological fluid Scios Inc. (US) 2009-09-09 — — EP disclosed
US-20090215182-A1 METHOD, COMPOSITION AND DEVICE FOR SAMPLING NATRIURETIC PEPTIDES IN A BIOLOGICAL FLUID QUIDEL CORPORATION 2009-08-27 — — US disclosed
EP-1858540-A2 STABILIZED COMPOSITIONS CONTAINING NATRIURETIC PEPTIDES Bio-Rad Laboratories, Inc. (US) 2007-11-28 — — EP disclosed
US-6037362-A CARBAZOLE DERIVATIVES; DEPROTECTING, AMINATION; ANTILIPEMIC AND ANTIDIABETIC AGENTS; B-ADRENALINE RECEPTOR AGONISTS; DIETETICS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-03-14 — — US disclosed
US-5973156-A Piperidine and tetrahydropyridine derivatives MERCK SHARP & DOME LTD. (GB) 1999-10-26 — — US disclosed
EP-0882707-A1 NOVEL TRICYCLIC COMPOUNDS AND DRUG COMPOSITIONS CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-12-09 — — EP disclosed
EP-0861245-A1 PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES MERCK SHARP & DOHME LTD. (GB) 1998-09-02 — — EP disclosed
WO-1997019073-A1 PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1997-05-29 — — WO disclosed
US-5459131-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1995-10-17 — — US disclosed
EP-0206714-B1 PROCESS FOR THE PREPARATION OF AN AMINE TERMINATED POLYBUTADIENE ELF ATOCHEM S.A. (FR) 1991-03-13 — — EP disclosed
EP-0206714-A1 Process for the preparation of an amine terminated polybutadiene ELF ATOCHEM S.A. (FR) 1986-12-30 — — EP disclosed
US-4065459-A SULFONATION PARCOR (FR) 1977-12-27 — — US disclosed
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