Phosphoramidon

Phosphoramidon

SCHEMBL40933

CC(C)C[C@H](NP(=O)(O)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 6/20 1.00
ACE P12821 3/20 1.00
MME P08473 1/20 1.00
LMNA P02545 1/20 0.74
ERAP2 Q6P179 4/20 0.53
ERAP1 Q9NZ08 3/20 0.51
IL1RN P18510 2/20 0.51
ANPEP P15144 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoramidon SCHEMBL17813729 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL9100804 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL4436662 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL117398 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL14503212 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL8189183 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL7155564 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL8029985 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL7300320 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
SCHEMBL20179087 0.87 ECE1 (0.78) ECE1ACEMMELMNAERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7601 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605384-B2 Uses INTRA-CELLULAR THERAPIES, INC. (US) 2026-04-21 US claimed
EP-4427588-A2 COMPOSITIONS FOR HEMOLYSIS AND COAGULATION REGULATION AND STABILIZATION OF EXTRACELLULAR VESICLES Streck LLC (US) 2024-09-11 EP claimed
US-20240189317-A1 ANTIVIRAL COMPOSITIONS AND METHODS ACADIA WOODS PARTNERS, LLC 2024-06-13 US claimed
EP-4308103-A1 ANTIVIRAL COMPOSITIONS AND METHODS AI Therapeutics, Inc. (US) 2024-01-24 EP claimed
US-20230338385-A1 NOVEL USES INTRA-CELLULAR THERAPIES, INC. 2023-10-26 US claimed
US-11759465-B2 Uses INTRA-CELLULAR THERAPIES, INC. (US) 2023-09-19 US claimed
US-11693006-B2 Blood profiling with protease inhibitors SANGUI BIO PTY. LTD (AU) 2023-07-04 US claimed
US-20230184786-A1 Methods of Detecting and Treating Immune Responses Associated with Viral Infection FORSYTH DENTAL INFIRMARY FOR CHILDREN, d/b/a THE FORSYTH INSTITUTE 2023-06-15 US claimed
CN-114814013-B Method for rapidly screening unknown chemical hazard residues in aquatic products based on high-resolution mass spectrum database 中国海洋大学 2023-06-02 CN claimed
US-11612667-B2 Enhanced in vivo targeting of radiolabelled peptides with the means of enzyme inhibitors ADVANCED ACCELERATOR APPLICATIONS USA INC (US) 2023-03-28 US claimed
WO-1993005809-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING NATRIURETIC PEPTIDES OR NEUTRAL ENDOPEPTIDASE INHIBITORS FOR TREATING OR PREVENTING MYOINTIMAL PROLIFERATION SCHERING CORPORATION (US) 1993-04-01 WO claimed
EP-0533913-A1 NOVEL ENDOPEPTIDASE THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 1993-03-31 EP claimed
EP-0533084-A1 Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating and preventing myointimal proliferation SCHERING CORPORATION (US) 1993-03-24 EP claimed
WO-1992018159-A1 USE OF NEUTRAL ENDOPEPTIDASE INHIBITORS IN THE TREATMENT OF NEPHROTOXICITY SCHERING CORPORATION (US) 1992-10-29 WO claimed
WO-1992018516-A1 NOVEL ENDOPEPTIDASE THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 1992-10-29 WO claimed
EP-0509442-A1 Use of neutral endopeptidase inhibitors in the treatment of nephrotoxicity SCHERING CORPORATION (US) 1992-10-21 EP claimed
WO-1992013564-A1 COMBINATION OF AN ANGIOTENSIN II ANTAGONIST OR RENIN INHIBITOR WITH A NEUTRAL ENDOPEPTIDASE INHIBITOR SCHERING CORPORATION (US) 1992-08-20 WO claimed
WO-1992013944-A1 ENDOTHELIN CONVERTING ENZYME BERLEX LABORATORIES, INC. (US) 1992-08-20 WO claimed
EP-0498361-A2 Combination of an angiotensin II antagonist or renin inhibitor with a neutral endopeptidase inhibitor SCHERING CORPORATION (US) 1992-08-12 EP claimed
EP-0348348-A2 Process for controlling plant pests CIBA-GEIGY AG (CH) 1989-12-27 EP claimed