Phosphoramidon

Phosphoramidon

SCHEMBL8029985

CC(C)C[C@H](NP(=O)(O)OC1O[C@H](C)[C@@H](O)[C@H](O)[C@@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 6/20 1.00
ACE P12821 3/20 1.00
MME P08473 1/20 1.00
LMNA P02545 1/20 0.74
ERAP2 Q6P179 4/20 0.53
ERAP1 Q9NZ08 3/20 0.51
IL1RN P18510 2/20 0.51
ANPEP P15144 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoramidon SCHEMBL17813729 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL9100804 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL4436662 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL117398 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL40933 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL14503212 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL8189183 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL7155564 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL7300320 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
SCHEMBL20179087 0.87 ECE1 (0.78) ECE1ACEMMELMNAERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983299-A1 COVALENTLY COUPLED TROPONIN COMPLEXES Medical Analysis Systems, Inc. (US) 2000-03-08 EP disclosed
WO-1998054219-A1 COVALENTLY COUPLED TROPONIN COMPLEXES MEDICAL ANALYSIS SYSTEMS INC. (US) 1998-12-03 WO disclosed