Phosphoramidon

Phosphoramidon

SCHEMBL8189183

CC(C)C[C@H](NP(=O)(O)OC1OC(C)C(O)C(O)C1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 6/20 1.00
ACE P12821 3/20 1.00
MME P08473 1/20 1.00
LMNA P02545 1/20 0.74
ERAP2 Q6P179 4/20 0.53
ERAP1 Q9NZ08 3/20 0.51
IL1RN P18510 2/20 0.51
ANPEP P15144 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoramidon SCHEMBL17813729 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL9100804 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL4436662 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL117398 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL40933 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL14503212 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL7155564 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL8029985 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
Phosphoramidon SCHEMBL7300320 1.00 ECE1 (1.00) ECE1ACEMMELMNAERAP2
SCHEMBL20179087 0.87 ECE1 (0.78) ECE1ACEMMELMNAERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160122691-A1 CLEANING COMPOSITIONS PROCTER & GAMBLE (US) 2016-05-05 US disclosed
US-8541354-B2 Catalytic laundry detergent composition comprising relatively low levels of water-soluble electrolyte THE PROCTER & GAMBLE COMPANY (US) 2013-09-24 US disclosed
US-20090209447-A1 CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2009-08-20 US disclosed
WO-2007025999-A1 USE OF AN AUREOLYSIN INHIBITOR FOR THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS CHARACTERISED BY COLONISATION WITH STAPHYLOCOCCUS AUREUS SERENTIS LIMITED (GB) 2007-03-08 WO disclosed
US-20070049518-A1 Novel method of treatment of inflammatory skin conditions SERENTIS LIMITED (GB) 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049518-A1 Novel method of treatment of inflammatory skin conditions MMP8, CUTA, MMP1 ECE1 532/4885ACE 713/4885MME 540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.