Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737479 | 0.89 | HSD17B10 (0.52) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL4093452 | 0.88 | TSHR (0.37) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL3913401 | 0.78 | ERN1 (0.41) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL13365218 | 0.77 | ACHE (0.44) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL9812457 | 0.76 | KDM4E (0.57) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL29173956 | 0.74 | AKR1C2 (0.60) | HSD17B10TTRALDH1A1KDM4EHPGD | |
| SCHEMBL2642163 | 0.72 | ACHE (0.42) | HSD17B10TSHRTTRRECQLACHE | |
| SCHEMBL9308747 | 0.71 | KDM4E (0.39) | HSD17B10CYP3A4ALDH1A1ACHEKDM4E | |
| SCHEMBL1965439 | 0.71 | HPGD (0.48) | HSD17B10TSHRCYP3A4RECQLALDH1A1 | |
| SCHEMBL7885118 | 0.71 | HSD17B10 (0.55) | HSD17B10TSHRCYP3A4TTRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293029-B2 | Colored conversion layers on metal surfaces | HENKEL AG & CO. KGAA (DE) | 2012-10-23 | — | — | US | disclosed |
| US-20090214883-A1 | CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION | HENKEL AG & CO. KGAA (DE) | 2009-08-27 | — | — | US | disclosed |
| US-20060173099-A1 | Colored conversion layers on metal surfaces | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-08-03 | — | — | US | disclosed |