SCHEMBL4093528

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3246657	1.00	KMT2A (0.41)	KMT2AMEN1MAPK14MAPK3HDAC4
	SCHEMBL3247284	0.90	MEN1 (0.40)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL3247287	0.90	MEN1 (0.40)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL3247407	0.90	MEN1 (0.41)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL3247405	0.90	MEN1 (0.41)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL4083108	0.90	MEN1 (0.41)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL11362162	0.90	MAPK14 (0.42)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL11961397	0.88	MEN1 (0.40)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL11353990	0.88	MEN1 (0.40)	KMT2AMEN1MAPK14HDAC4HDAC6
	SCHEMBL3249282	0.88	MEN1 (0.40)	KMT2AMEN1MAPK14HDAC4HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.