Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2416924 | 1.00 | MAPT (0.45) | MAPTHPGDKDM4EALOX15HSD17B10 | |
| SCHEMBL2409788 | 0.93 | CA12 (0.44) | HSD17B10TRPV1APP | |
| SCHEMBL2417274 | 0.86 | PSMB11 (0.48) | MAPTHPGDKDM4EALOX15HSD17B10 | |
| SCHEMBL2417275 | 0.86 | PSMB11 (0.48) | MAPTHPGDKDM4EALOX15HSD17B10 | |
| SCHEMBL2416682 | 0.83 | PPARA (0.41) | MAPK1FAAHPPARA | |
| SCHEMBL2416686 | 0.81 | ALOX15 (0.49) | MAPTHPGDALOX15HSD17B10CYP3A4 | |
| SCHEMBL2412575 | 0.81 | LMNA (0.52) | MAPTLMNATP53POLBMAPK1 | |
| SCHEMBL2412578 | 0.78 | POLM (0.46) | MAPTHPGDALOX15HSD17B10CYP1A2 | |
| SCHEMBL2384369 | 0.78 | ESR1 (0.44) | KDM4EHSD17B10LMNATP53CYP1A2 | |
| SCHEMBL5699327 | 0.78 | ESR1 (0.44) | KDM4EHSD17B10LMNATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098246-B2 | Natural compounds and their derivatives for the prevention and treatment of cardiovascular, hepatic and renal diseases and for cosmetic applications | PULEVA BIOTECH, S.A. (ES) | 2006-08-29 | — | — | US | disclosed |
| EP-1516866-B1 | NATURAL COMPOUNDS AND DERIVATIVES THEREOF FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, HEPATIC AND RENAL DISEASES AND FOR COSMETIC APPLICATIONS | PULEVA BIOTECH SA (ES) | 2006-07-12 | — | — | EP | disclosed |
| EP-1494658-B1 | NATURAL PHENOLIC PRODUCTS AND DERIVATIVES THEREOF FOR PROTECTION AGAINST NEURODEGENERATIVE DISEASES | PULEVA BIOTECH SA (ES) | 2006-01-04 | — | — | EP | disclosed |
| EP-1516866-A9 | NATURAL COMPOUNDS AND DERIVATIVES THEREOF FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, HEPATIC AND RENAL DISEASES AND FOR COSMETIC APPLICATIONS | PULEVA BIOTECH, S.A. (ES) | 2005-10-05 | — | — | EP | disclosed |
| EP-1516866-A1 | NATURAL COMPOUNDS AND DERIVATIVES THEREOF FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, HEPATIC AND RENAL DISEASES AND FOR COSMETIC APPLICATIONS | PULEVA BIOTECH, S.A. (ES) | 2005-03-23 | — | — | EP | disclosed |
| EP-1494658-A1 | NATURAL PHENOLIC PRODUCTS AND DERIVATIVES THEREOF FOR PROTECTION AGAINST NEURODEGENERATIVE DISEASES | PULEVA BIOTECH, S.A. (ES) | 2005-01-12 | — | — | EP | disclosed |
| US-20030236202-A1 | Natural products and derivatives thereof for protection against neurodegenerative diseases | PULEVA BIOTECH, S.A. (ES) | 2003-12-25 | — | — | US | disclosed |
| US-20030225160-A1 | Natural compounds and their derivatives for the prevention and treatment of cardiovascular, hepatic and renal diseases and for cosmetic applications | PULEVA BIOTECH S.A. (ES) | 2003-12-04 | — | — | US | disclosed |
| WO-2003082259-A1 | NATURAL PHENOLIC PRODUCTS AND DERIVATIVES THEREOF FOR PROTECTION AGAINST NEURODEGENERATIVE DISEASES | PULEVA BIOTECH, S.A. (ES) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225160-A1 | Natural compounds and their derivatives for the prevention and treatment of cardiovascular, hepatic and renal diseases and for cosmetic applications | LIPC, FABP1, NR1H2 | MAPT 4558/4885HPGD 1786/4885KDM4E 3373/4885 |
| US-20030236202-A1 | Natural products and derivatives thereof for protection against neurodegenerative diseases | SNCA, HTT, PARK7 | MAPT 9/4885HPGD 652/4885KDM4E 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.