Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2678604 | 0.99 | MAPT (0.37) | MAPTLMNANPSR1SLC6A2SLC6A4 | |
| SCHEMBL2677306 | 0.92 | SLC6A2 (0.33) | MAPTLMNASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2677302 | 0.91 | SLC6A2 (0.33) | MAPTLMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2677539 | 0.88 | MAPT (0.41) | MAPTLMNASMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL2677535 | 0.87 | MAPT (0.40) | MAPTLMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2678603 | 0.87 | ALDH1A1 (0.48) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2678209 | 0.86 | USP7 (0.34) | MAPTLMNASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2678600 | 0.86 | ALDH1A1 (0.47) | MAPTLMNANPSR1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2678205 | 0.86 | USP7 (0.34) | MAPTLMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1886632 | 0.84 | SIRT6 (0.42) | MAPTLMNASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023745-A1 | Substituted Pyrazolo[4,3-c]Pyridine Derivatives Active as Kinase Inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023745-A1 | Substituted Pyrazolo[4,3-c]Pyridine Derivatives Active as Kinase Inhibitors | MAP3K3, MAP3K1, MAP3K19 | MAPT 2600/4885LMNA 3253/4885NPSR1 4360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.