SCHEMBL409423

SCHEMBL409423

CCCCCCCC[Si](O[SiH](C)C)(O[SiH](C)C)O[SiH](C)C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.38
LPAR2 Q9HBW0 3/20 0.31
LPAR3 Q9UBY5 3/20 0.31
DNM1 Q05193 5/20 0.31
ALDH1A1 P00352 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013380 1.00 LMNA (0.39) LMNATSHRTHRBLPAR2LPAR3
SCHEMBL5701603 1.00 LMNA (0.39) LMNATSHRTHRBLPAR2LPAR3
SCHEMBL5701843 1.00 LMNA (0.39) LMNATSHRTHRBLPAR2LPAR3
SCHEMBL5701937 0.89 LMNA (0.48) LMNATSHRTHRB
SCHEMBL5701917 0.89 LMNA (0.48) LMNATSHRTHRB
SCHEMBL5701507 0.87 LMNA (0.35) LMNATSHRTHRBALDH1A1
SCHEMBL5701371 0.87 LMNA (0.35) LMNATSHRTHRBALDH1A1
SCHEMBL20078068 0.82
SCHEMBL5251723 0.79
SCHEMBL18389668 0.79 TSHR (0.36) LMNATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2244689-B1 DEPOSITION OF LIPOPHILIC ACTIVE MATERIAL IN SURFACTANT CONTAINING COMPOSITIONS DOW CORNING (US) 2017-08-23 EP disclosed
EP-2358856-B1 PROCESS FOR PREPARING SILICATE SHELL MICROCAPSULES DOW CORNING (US) 2017-03-01 EP disclosed
US-9192549-B2 Process for preparing silicate shell microcapsules DOW CORNING CORPORATION (US) 2015-11-24 US disclosed
US-20150174017-A1 PROCESS FOR PREPARING SILICATE SHELL MICROCAPSULES DOW SILICONES CORPORATION 2015-06-25 US disclosed
US-20150174018-A1 FABRIC AND FIBRE CONDITIONING ADDITIVES DOW CORNING CORPORATION 2015-06-25 US disclosed
US-9005639-B2 Process for preparing silicate shell microcapsules DOW CORNING CORPORATION (US) 2015-04-14 US disclosed
US-9005640-B2 Fabric and fibre conditioning additives DOW CORNING CORPORATION (US) 2015-04-14 US disclosed
US-20120021023-A1 Process For Preparing Silicate Shell Microcapsules DOW SILICONES CORPORATION 2012-01-26 US disclosed
EP-2358856-A2 PROCESS FOR PREPARING SILICATE SHELL MICROCAPSULES Dow Corning Corporation (US) 2011-08-24 EP disclosed
EP-2337838-A1 FABRIC AND FIBRE CONDITIONING ADDITIVES Dow Corning Corporation (US) 2011-06-29 EP disclosed
US-7135513-B2 Adding to antimisting additive which is a branched organosilicon compound for reducing formation of aerosol during coating of substrates WACKER CHEMIE AG (DE) 2006-11-14 US disclosed
EP-1481030-B1 BRANCHED ORGANOSILICON COMPOUNDS AS ANTIMISTING ADDITIVES FOR SILICONE COATING COMPOSITIONS WACKER CHEMIE GMBH (DE) 2005-10-05 EP disclosed
US-20050106399-A1 Branched organosilicon compounds as antimisting additives for silicone coating compositions WACKER-CHEMIE GMBH (DE) 2005-05-19 US disclosed
EP-1471995-A1 ENCAPSULATION PROCESS AND ENCAPSULATED COMPOSITIONS Dow Corning Corporation (US) 2004-11-03 EP disclosed
WO-2003066209-A1 ENCAPSULATION PROCESS AND ENCAPSULATED COMPOSITIONS DOW CORNING CORPORATION (US) 2003-08-14 WO disclosed
EP-0832935-B1 Cross-linkable compositions containing organopolysiloxanes having aliphatic unsaturated hydrocarbon groups WACKER CHEMIE GMBH (DE) 1999-01-13 EP disclosed
EP-0851000-A2 Curable adhesive organosilicon compositions DOW CORNING LIMITED (GB) 1998-07-01 EP disclosed
US-5760145-A RELEASE AGENTS WACKER-CHEMIE GMBH (DE) 1998-06-02 US disclosed
EP-0832935-A1 Cross-linkable compositions containing organopolysiloxanes having aliphatic unsaturated hydrocarbon groups Wacker-Chemie GmbH (DE) 1998-04-01 EP disclosed
US-5493040-A ALKYLTRIS/DIMETHYLSILOXY/SILANES AS CHEMICAL INTERMEDIATES DOW CORNING CORPORATION (US) 1996-02-20 US disclosed