Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409423 | 1.00 | LMNA (0.39) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL5701603 | 1.00 | LMNA (0.39) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL5701843 | 1.00 | LMNA (0.39) | LMNATSHRTHRBLPAR2LPAR3 | |
| SCHEMBL5701937 | 0.89 | LMNA (0.48) | LMNATSHRTHRB | |
| SCHEMBL5701917 | 0.89 | LMNA (0.48) | LMNATSHRTHRB | |
| SCHEMBL5701507 | 0.87 | LMNA (0.35) | LMNATSHRTHRBALDH1A1 | |
| SCHEMBL5701371 | 0.87 | LMNA (0.35) | LMNATSHRTHRBALDH1A1 | |
| SCHEMBL20078068 | 0.82 | — | — | |
| SCHEMBL5251723 | 0.79 | — | — | |
| SCHEMBL18389668 | 0.79 | TSHR (0.36) | LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5493040-A | ALKYLTRIS/DIMETHYLSILOXY/SILANES AS CHEMICAL INTERMEDIATES | DOW CORNING CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |