Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL30717997 | 0.96 | ALDH1A1 (0.61) | ALDH1A1ALOX15FFAR3HDAC3HDAC1 | |
| Phthalic Acid SCHEMBL8155 | 0.96 | ALDH1A1 (0.61) | ALDH1A1ALOX15FFAR3HDAC3HDAC1 | |
| Phthalic Acid SCHEMBL121925 | 0.90 | ALDH1A1 (0.64) | ALDH1A1ALOX15HDAC8HPGDHSD17B10 | |
| Phthalic Acid SCHEMBL9164708 | 0.85 | ALDH1A1 (0.64) | ALDH1A1ALOX15FFAR3HDAC8HPGD | |
| Salicylic Acid SCHEMBL28044508 | 0.85 | ALDH1A1 (0.67) | ALDH1A1ALOX15FFAR3HDAC3HDAC1 | |
| Toluic Acid SCHEMBL28104690 | 0.85 | KMT2A (0.53) | ALDH1A1ALOX15FFAR3HDAC3HDAC1 | |
| Butyric Acid SCHEMBL27907905 | 0.83 | ALDH1A1 (0.53) | ALDH1A1ALOX15FFAR3HDAC3HDAC1 | |
| Phthalic Acid SCHEMBL28283200 | 0.83 | ALDH1A1 (0.67) | ALDH1A1ALOX15HDAC8HPGDHSD17B10 | |
| Phthalic Acid SCHEMBL1482851 | 0.83 | ALDH1A1 (0.74) | ALDH1A1ALOX15HDAC8HPGDKDM4E | |
| Phthalic Acid SCHEMBL22217134 | 0.83 | ALDH1A1 (0.74) | ALDH1A1ALOX15HDAC8HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845052-B2 | Flavor encapsulation using electrostatic atomization | FONA TECHNOLOGIES, LLC (US) | 2023-12-19 | — | — | US | claimed |
| CN-112293715-B | Composition for endowing food with milk flavor, enzymolysis aroma-enhancing milk fat and product and preparation method thereof | 内蒙古伊利实业集团股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-114568676-A | Composition for endowing food with cheese flavor and preparation method and application thereof | 内蒙古伊利实业集团股份有限公司 | 2022-06-03 | — | — | CN | claimed |
| US-20220105485-A1 | Flavor Encapsulation Using Electrostatic Atomization | FONA TECHNOLOGIES, LLC | 2022-04-07 | — | — | US | claimed |
| US-11235303-B2 | Flavor encapsulation using electrostatic atomization | FONA TECHNOLOGIES, LLC (US) | 2022-02-01 | — | — | US | claimed |
| CN-112293715-A | Composition for endowing food with milk-flavor, enzymatic flavored milk fat and product and preparation method thereof | 内蒙古伊利实业集团股份有限公司 | 2021-02-02 | — | — | CN | claimed |
| US-4134809-A | GLYCIDYL ACRYLATES, ADHESIVE METAL COATINGS | EASTMAN KODAK COMPANY (US) | 1979-01-16 | — | — | US | claimed |
| CN-110475473-B | Compound containing monoterpene/phenylpropanoid, preparation method and application thereof as pesticide | 奇特利奇公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-112996590-B | Microencapsulation using high voltage low current high frequency ac spray atomization | 福纳技术有限责任公司 | 2024-04-09 | — | — | CN | disclosed |
| US-11845052-B2 | Flavor encapsulation using electrostatic atomization | FONA TECHNOLOGIES, LLC (US) | 2023-12-19 | — | — | US | disclosed |
| CN-112293715-B | Composition for endowing food with milk flavor, enzymolysis aroma-enhancing milk fat and product and preparation method thereof | 内蒙古伊利实业集团股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-114568676-A | Composition for endowing food with cheese flavor and preparation method and application thereof | 内蒙古伊利实业集团股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| US-20220105485-A1 | Flavor Encapsulation Using Electrostatic Atomization | FONA TECHNOLOGIES, LLC | 2022-04-07 | — | — | US | disclosed |
| US-20140303089-A1 | Plant HSP70 for Use in the Treatment of Food Allergy | ALFA BIOGENE INTERNATIONAL B.V. (DE) | 2014-10-09 | — | — | US | disclosed |
| EP-2673050-A1 | PLANT HSP70 FOR USE IN THE TREATMENT OF FOOD ALLERGY | Alfa Biogene International B.V. (DE) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107095-A1 | PLANT HSP70 FOR USE IN THE TREATMENT OF FOOD ALLERGY | ALFA BIOGENE INTERNATIONAL B.V. (DE) | 2012-08-16 | — | — | WO | disclosed |
| US-20120021971-A1 | Functional Food Product Comprising Heat Shock Protein or a Hydrolysate Thereof | ALFA BIOGENE INTERNATIONAL B.V. (DE) | 2012-01-26 | — | — | US | disclosed |
| EP-2391229-A1 | FUNCTIONAL FOOD PRODUCT COMPRISING HEAT SHOCK PROTEIN OR A HYDROLYSATE THEREOF | Alfa Biogene International B.V. (DE) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010086418-A1 | FUNCTIONAL FOOD PRODUCT COMPRISING HEAT SHOCK PROTEIN OR A HYDROLYSATE THEREOF | ALFA BIOGENE INTERNATIONAL B.V. (DE) | 2010-08-05 | — | — | WO | disclosed |
| US-4134809-A | GLYCIDYL ACRYLATES, ADHESIVE METAL COATINGS | EASTMAN KODAK COMPANY (US) | 1979-01-16 | — | — | US | disclosed |