Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993614 | 0.81 | FFAR1 (0.50) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 | |
| SCHEMBL1609920 | 0.80 | L3MBTL1 (0.40) | FFAR1SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL10888790 | 0.80 | AOC3 (0.58) | SLC6A4SLC6A2SLC6A3AOC3ADRB2 | |
| SCHEMBL13899269 | 0.78 | FFAR1 (0.45) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 | |
| SCHEMBL10487689 | 0.76 | SLC6A4 (0.49) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 | |
| SCHEMBL6158575 | 0.75 | SLC6A2 (0.51) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 | |
| SCHEMBL3939065 | 0.74 | SLC6A4 (0.48) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 | |
| SCHEMBL18722667 | 0.74 | SLC6A2 (0.50) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 | |
| SCHEMBL27536783 | 0.71 | SLC6A2 (0.47) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 | |
| SCHEMBL14791731 | 0.69 | AOC3 (0.59) | FFAR1SLC6A4SLC6A2SLC6A3AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507832-B2 | Triazole PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-20070112045-A1 | Triazole ppar modulators | ELI LILLY AND COMPANY | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112045-A1 | Triazole ppar modulators | PPARD, PPARA, PPARG | FFAR1 21/4885SLC6A4 2522/4885SLC6A2 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.