Sugi Predict

Sugi Predict / Compounds / SCHEMBL6158575

SCHEMBL6158575

SCHEMBL6158575

CCOC(OCC)c1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.51
▸ SLC6A4 P31645 1/20 0.51
▸ SLC6A3 Q01959 1/20 0.51
▸ ACHE P22303 7/20 0.49
▸ PTGS2 P35354 7/20 0.49
▸ BCHE P06276 6/20 0.49
▸ LMNA P02545 2/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ ADRB2 P07550 1/20 0.43
▸ FFAR1 O14842 1/20 0.41
▸ IDO1 P14902 1/20 0.40
▸ TDO2 P48775 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ TSHR P16473 2/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ HIF1A Q16665 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ AOC3 Q16853 1/20 0.39
▸ TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6394314 0.88 PTGS2 (0.57) SLC6A2SLC6A4SLC6A3ACHEPTGS2
SCHEMBL10535136 0.84 PTGS2 (0.50) SLC6A2SLC6A4SLC6A3ACHEPTGS2
SCHEMBL18722667 0.80 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3LMNASMN1; SMN2
SCHEMBL3906858 0.79 ACHE (0.50) ACHEPTGS2BCHEFFAR1NPC1
SCHEMBL508188 0.79 PTGS2 (0.50) SLC6A2SLC6A4SLC6A3ACHEPTGS2
SCHEMBL10487689 0.78 SLC6A4 (0.49) SLC6A2SLC6A4SLC6A3LMNASMN1; SMN2
SCHEMBL10761397 0.78 SMN1; SMN2 (0.42) SLC6A2SLC6A4SLC6A3LMNASMN1; SMN2
SCHEMBL17181664 0.78 ALOX15 (0.44) SLC6A2SLC6A4SLC6A3ACHEPTGS2
SCHEMBL6204102 0.77 PTGS2 (0.49) SLC6A2SLC6A4SLC6A3ACHEPTGS2
SCHEMBL12296727 0.77 PTGS2 (0.49) SLC6A2SLC6A4SLC6A3ACHEPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106231-B Adsorbent resin and preparation method thereof 泉州师范学院 2023-11-24 — — CN disclosed
WO-2020034477-A1 POROUS ORGANIC CAGE LIGAND CONTAINING P AND N, PREPARATION THEREFOR AND USE THEREOF 中国科学院大连化学物理研究所 2020-02-20 — — WO disclosed
WO-2020034476-A1 POROUS ORGANIC CAGE LIGAND CONTAINING P AND N AND COMPLEX CATALYST AND APPLICATION 中国科学院大连化学物理研究所 2020-02-20 — — WO disclosed
CN-106279264-B A kind of preparation method of alpha-alkoxy base p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2019-05-24 — — CN disclosed
CN-106279275-B A kind of process for catalytic synthesis of alpha-alkoxy base p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2018-11-13 — — CN disclosed
CN-106279264-A A kind of preparation method of α alkoxyl p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2017-01-04 — — CN disclosed
CN-106279275-A A kind of process for catalytic synthesis of α alkoxyl p-chlorobenzyl phosphonate ester 江苏七洲绿色化工股份有限公司 2017-01-04 — — CN disclosed
CN-104230879-B A kind of 2-((4R, 6S)-6-formoxyl-2,2-disubstituted-1,3-dioxane-4-base) acetas preparation method 新发药业有限公司 2016-08-24 — — CN disclosed
US-9227900-B2 Method for preparing 1-(4-chlorophenyl)-2-cyclopropyl-1-propanone and intermediate thereof JIANGSU CHENGYANG CROP SCIENCE CO., LTD. (CN) 2016-01-05 — — US disclosed
CN-102942465-B The Preparation Method And Their Intermediate of 1-(4-chloro-phenyl-)-2-cyclopropyl-1-acetone Jiangsu Chengyang Crop Science Co.,Ltd. (CN) 2015-10-28 — — CN disclosed
US-20040049050-A1 Method for producing formylphenylboronic acids EUTICALS GMBH (DE) 2004-03-11 — — US disclosed
EP-1343792-A1 METHOD FOR PRODUCING FORMYLPHENYLBORONIC ACIDS Clariant GmbH (DE) 2003-09-17 — — EP disclosed
EP-1070718-B1 Method for Preparing Grignard Reagents and new Grignard Reagents BAYER AG (DE) 2003-03-05 — — EP disclosed
US-20020161229-A1 Process for the synthesis of organomagnesium compounds using catalysts STUDIENGESELLSCHAFT KOHLE MBH (DE) 2002-10-31 — — US disclosed
WO-2002048155-A1 METHOD FOR PRODUCING FORMYLPHENYLBORONIC ACIDS CLARIANT GMBH (DE) 2002-06-20 — — WO disclosed
US-6296788-B1 REACTING HALOGENATED ALDEHYDE WITH SECONDARY MONOAMINE TO FORM AMINAL; METALLIZATION WITH MAGNESIUM BAYER AKTIENGESELLSCHAFT (DE) 2001-10-02 — — US disclosed
CN-1284506-A Prep. of Grignard reagent and new grignard reagent BAYER AG (DE) 2001-02-21 — — CN disclosed
EP-1070718-A1 Method for Preparing Grignard Reagents and new Grignard Reagents Bayer Aktiengesellschaft (DE) 2001-01-24 — — EP disclosed
US-4656192-A Tropolone derivatives, processes for the preparation thereof and the use thereof as anti-tumor agents MECT CORPORATION (JP) 1987-04-07 — — US disclosed
US-3936438-A INOTROPIC WARNER-LAMBERT COMPANY (US) 1976-02-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040049050-A1 Method for producing formylphenylboronic acids MAOB, BLVRB, FOSB SLC6A2 863/4885SLC6A4 2183/4885SLC6A3 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.