SCHEMBL4095126

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2681364	0.89	MAP4K4 (0.49)	LRRK2MAP4K4METMST1RCDK1
	SCHEMBL2681185	0.89	MET (0.54)	LRRK2MAP4K4METMST1RCDK1
	SCHEMBL4101039	0.86	MAPK1 (0.46)	LRRK2MAP4K4METMST1RCDK1
	SCHEMBL4100016	0.86	MET (0.54)	LRRK2MAP4K4METMST1RCDK1
	Trifluoroacetic Acid SCHEMBL992817	0.83	MET (0.51)	LRRK2MAP4K4METMST1RCDK1
	SCHEMBL4090329	0.82	PRMT5 (0.40)	CDK1CDK2MKNK1MKNK2PDPK1
	SCHEMBL2680532	0.81	PKN1 (0.53)	LRRK2MAP4K4METCDK1CDK2
	SCHEMBL991709	0.80	MET (0.59)	METMST1RMAPK1
	SCHEMBL16390901	0.80	SLC2A1 (0.49)	LRRK2MAP4K4METCDK1CDK2
	SCHEMBL16390736	0.80	MET (0.47)	LRRK2MAP4K4METMST1RCDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.