Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099177 | 0.78 | SMN1; SMN2 (0.42) | HPGDHSD17B10KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1451490 | 0.67 | ALDH1A1 (0.53) | TDP1ALDH1A1GAA | |
| SCHEMBL12929282 | 0.67 | ALDH1A1 (0.60) | KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4105713 | 0.66 | ALDH1A1 (0.36) | KMT2ASMN1; SMN2MAPTKDM4ELMNA | |
| SCHEMBL9278739 | 0.66 | KMT2A (0.35) | KMT2ASMN1; SMN2TDP1CYP3A4ALDH1A1 | |
| SCHEMBL3192700 | 0.64 | KMT2A (0.62) | KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4100020 | 0.64 | ALDH1A1 (0.34) | HSD17B10KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL5837417 | 0.64 | ALDH1A1 (0.57) | KMT2ASMN1; SMN2KDM4ETDP1ALDH1A1 | |
| SCHEMBL5837423 | 0.64 | ALDH1A1 (0.57) | KMT2ASMN1; SMN2KDM4ETDP1ALDH1A1 | |
| SCHEMBL11676453 | 0.64 | HPGD (0.65) | HPGDKMT2ASMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209705-A1 | THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM | JSR CORPORATION (JP) | 2009-08-20 | — | — | US | disclosed |
| US-7449532-B2 | Cycloolefin copolymer obtained by ring-opening polymerization, use thereof, and process for producing retardation plate comprising the copolymer | JSR CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20070179264-A1 | Copolymer of 8-methyl-8-methoxycarbonyltetracyclo[4.4.0.12,5.17,10]-3-dodecene or derivative with tricyclo[4.3.0.12,5]deca-3,7-diene or derivative; can be stretched even at low temperature around the glass transition temperature without causing cloudiness; excellent heat resistance and optical properties | JSR CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1795559-A1 | THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM | JSR Corporation (JP) | 2007-06-13 | — | — | EP | disclosed |