Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4095474 | 0.78 | HPGD (0.36) | SMN1; SMN2HPGDKDM4EALDH1A1CYP3A4 | |
| SCHEMBL2705426 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMTSHRHPGDKDM4E | |
| SCHEMBL16900345 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2KCNH2PKMTSHRHPGD | |
| SCHEMBL4156385 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2PKMTSHRHPGDKDM4E | |
| SCHEMBL9278739 | 0.71 | KMT2A (0.35) | SMN1; SMN2PKMALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL17992238 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMTSHRHPGDKDM4E | |
| SCHEMBL222067 | 0.67 | TSHR (0.36) | TSHRKDM4EALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL9063836 | 0.67 | ALDH1A1 (0.38) | SMN1; SMN2TSHRHTTALDH1A1TDP1 | |
| SCHEMBL2340043 | 0.66 | KCNH2 (0.49) | SMN1; SMN2KCNH2TSHRHPGDKDM4E | |
| SCHEMBL27207905 | 0.66 | MAPK1 (0.49) | KCNH2TSHRHPGDKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209705-A1 | THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM | JSR CORPORATION (JP) | 2009-08-20 | — | — | US | disclosed |
| US-7449532-B2 | Cycloolefin copolymer obtained by ring-opening polymerization, use thereof, and process for producing retardation plate comprising the copolymer | JSR CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20070179264-A1 | Copolymer of 8-methyl-8-methoxycarbonyltetracyclo[4.4.0.12,5.17,10]-3-dodecene or derivative with tricyclo[4.3.0.12,5]deca-3,7-diene or derivative; can be stretched even at low temperature around the glass transition temperature without causing cloudiness; excellent heat resistance and optical properties | JSR CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1795559-A1 | THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM | JSR Corporation (JP) | 2007-06-13 | — | — | EP | disclosed |