SCHEMBL4095689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13849192	0.93	FLT3 (0.46)	FLT3PKN1PKN2SIRT2SIRT1
	SCHEMBL4104351	0.88	FLT3 (0.56)	FLT3CHEK1SMYD3FGFR1FGFR2
	SCHEMBL13849231	0.87	FLT3 (0.50)	FLT3CHEK1SMYD3FGFR1FGFR2
	SCHEMBL13849241	0.83	FLT3 (0.47)	FLT3CHEK1SMYD3FGFR1DHODH
	SCHEMBL13849246	0.83	FLT3 (0.49)	FLT3CHEK1SMYD3DHODH
	SCHEMBL13849238	0.82	FLT3 (0.48)	FLT3PKN2CHEK1SMYD3FGFR1
	SCHEMBL4090783	0.82	CHEK1 (0.56)	FLT3CHEK1SMYD3FGFR1BRD4
	SCHEMBL4104292	0.81	CHEK1 (0.47)	FLT3CHEK1SMYD3DHODH
	SCHEMBL13849237	0.81	CHEK1 (0.47)	FLT3CHEK1SMYD3DHODH
	SCHEMBL13849228	0.81	CHEK1 (0.47)	FLT3CHEK1SMYD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.