Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096012 | 0.92 | MGLL (0.63) | MGLLHTR2BMAPK7CHEK2 | |
| SCHEMBL4087324 | 0.87 | HTR2B (0.53) | MGLLHTR2BCHEK2 | |
| SCHEMBL4449950 | 0.86 | MGLL (0.47) | MGLLCHEK2 | |
| SCHEMBL4085565 | 0.83 | HTR2B (0.56) | MGLLHTR2B | |
| SCHEMBL4081522 | 0.80 | MGLL (0.53) | MGLLHTR2BCHEK2 | |
| SCHEMBL4081678 | 0.80 | SCD (0.52) | MGLLHTR2BMAPK8MAPK10 | |
| SCHEMBL4087327 | 0.79 | CHEK2 (0.63) | MGLLHTR2BCHEK2 | |
| SCHEMBL4449954 | 0.78 | CHEK2 (0.52) | MGLLCHEK2 | |
| SCHEMBL20897434 | 0.77 | MGLL (1.00) | MGLL | |
| SCHEMBL4092142 | 0.75 | IP6K1 (0.51) | MGLLHTR2BCHEK2MAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090017036-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | JUNG BIRGIT | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017036-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | BDKRB2, EDNRB, GRK5 | MGLL 1967/4885HTR2B 964/4885MAPK7 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.