Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.84 |
| ▸ | KDR | P35968 | 7/20 | 0.65 |
| ▸ | EPHB4 | P54760 | 6/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.65 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.64 |
| ▸ | FLT1 | P17948 | 1/20 | 0.64 |
| ▸ | FLT4 | P35916 | 2/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | INSR | P06213 | 1/20 | 0.61 |
| ▸ | FBP1 | P09467 | 1/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.61 |
| ▸ | CLK1 | P49759 | 1/20 | 0.61 |
| ▸ | TEK | Q02763 | 1/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.61 |
| ▸ | CIT | O14578 | 1/20 | 0.61 |
| ▸ | GAK | O14976 | 1/20 | 0.61 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704818 | 0.94 | KDR (0.73) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL29623391 | 0.94 | KDR (0.73) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL120714 | 0.94 | KDR (0.73) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL29623536 | 0.91 | EGFR (1.00) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL185721 | 0.91 | EGFR (1.00) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL13606795 | 0.90 | EGFR (0.69) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL1446083 | 0.89 | KDR (0.81) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL1446086 | 0.89 | KDR (0.81) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL1446388 | 0.89 | KDR (0.81) | EGFRKDREPHB4ERBB2EPHA2 | |
| SCHEMBL4089106 | 0.88 | EGFR (0.64) | EGFRKDREPHB4ERBB2EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090017036-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | JUNG BIRGIT | 2009-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017036-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS | BDKRB2, EDNRB, GRK5 | EGFR 53/4885KDR 436/4885EPHB4 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.