Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085420 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL4080908 | 0.74 | TLR2 (0.50) | ALDH1A1KDM4ESMN1; SMN2NPSR1HPGD | |
| SCHEMBL4080036 | 0.67 | GAA (0.97) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL4091261 | 0.64 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL4090895 | 0.62 | TLR2 (0.55) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4083898 | 0.61 | TLR2 (0.53) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4085480 | 0.61 | PDE4D (0.55) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL24310740 | 0.60 | HDAC4 (0.62) | ALDH1A1HTTSMN1; SMN2NPSR1GAA | |
| SCHEMBL2163243 | 0.60 | CXCR2 (0.49) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL16132889 | 0.60 | HDAC4 (1.00) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338623-B2 | N-{3-[(2,5-dimethylmorpholin-4-yl)carbonyl]-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl}hexahydro-2,5-methanopentalene-3a(1H)-carboxamide; CB2 receptors ligand; antiinflammatory, analgesic agent; autoimmune diseases; neuroprotectants | ABBVIE INC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | ALDH1A1 1504/4885MEN1 3065/4885KMT2A 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.