SCHEMBL4096716

SCHEMBL4096716

CC(C)(C)N(C[C@H](O)CCl)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4096717 1.00 MEN1 (0.31) MEN1HTTKMT2AL3MBTL1CA1
SCHEMBL20974178 0.87 MEN1 (0.34) MEN1HTTKMT2AL3MBTL1
SCHEMBL2788268 0.82 ACACB (0.33) MEN1HTTKMT2AL3MBTL1
SCHEMBL18340854 0.82 ACACB (0.33) MEN1HTTKMT2AL3MBTL1
SCHEMBL20480362 0.80 GABRR1 (0.40) MEN1HTTKMT2AL3MBTL1
SCHEMBL20974323 0.80 GABRR1 (0.40) MEN1HTTKMT2AL3MBTL1
SCHEMBL1023140 0.80 GABRR1 (0.40) MEN1HTTKMT2AL3MBTL1
SCHEMBL9129576 0.79 MEN1 (0.34) MEN1HTTKMT2AL3MBTL1
SCHEMBL16699764 0.78 THRB (0.34) MEN1HTTKMT2AL3MBTL1
SCHEMBL13731404 0.77 MEN1 (0.33) MEN1HTTKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2766373-B1 SILA ANALOGS OF OXAZOLIDINONE DERIVATIVES AND SYNTHESIS THEREOF COUNCIL SCIENT IND RES (IN) 2016-08-17 EP claimed
EP-1328509-B1 METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS PHARMACIA & UPJOHN CO LLC (US) 2006-03-22 EP claimed
US-20090221655-A1 ANTIBACTERIAL AGENTS PITZER, INC. (US) 2009-09-03 US disclosed
US-6972286-B2 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle PHARMACIA AND UPJOHN COMPANY (US) 2005-12-06 US disclosed
US-20040186293-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle JOHNSON PAUL D (US) 2004-09-23 US disclosed
US-20040176609-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle JOHNSON PAUL D (US) 2004-09-09 US disclosed
US-20020133021-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle PHARMACIA & UPJOHN COMPANY 2002-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133021-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle OXA1L, CDK16, MT-ND6 MEN1 2504/4885HTT 2819/4885KMT2A 3354/4885
US-20090221655-A1 ANTIBACTERIAL AGENTS OXSR1, CBR3, AOC3 MEN1 3546/4885HTT 2255/4885KMT2A 3830/4885
US-20040186293-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle OXA1L, CDK16, MT-ND6 MEN1 2504/4885HTT 2819/4885KMT2A 3354/4885
US-20040176609-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle OXA1L, CDK16, MT-ND6 MEN1 2504/4885HTT 2819/4885KMT2A 3354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.