SCHEMBL4097006

SCHEMBL4097006

Cc1cc(C(=O)CCc2sc(-c3ccc(C(F)(F)F)cc3)cc2C(C)C)ccc1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
GPR52 Q9Y2T5 2/20 0.35
FFAR1 O14842 2/20 0.35
HSD11B1 P28845 1/20 0.34
ESRRG P62508 1/20 0.34
PPARD Q03181 2/20 0.34
PPARA Q07869 2/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
HSP90AA1 P07900 1/20 0.34
CRHBP P24387 1/20 0.34
KMT2A Q03164 1/20 0.34
CRHR2 Q13324 1/20 0.34
CCR1 P32246 1/20 0.34
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
GCGR P47871 1/20 0.34
GIPR P48546 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4095805 0.89 CCR1 (0.38) HSD17B1HSD17B2FFAR1HSD11B1ESRRG
SCHEMBL4327180 0.87 PPARD (0.47) FFAR1PPARDPPARAGCGRGIPR
SCHEMBL24656247 0.85 PPARD (0.40) PPARDPPARAPPARG
SCHEMBL30003690 0.85 PPARD (0.40) PPARDPPARAPPARG
SCHEMBL4336571 0.85 PPARD (0.40) FFAR1PPARDPPARAMAPTKDM4E
SCHEMBL1765904 0.85 PPARD (0.51) PPARDPPARAPPARG
SCHEMBL24656252 0.84 PPARD (0.37) PPARDPPARAMAPTPPARG
SCHEMBL1765881 0.84 PPARA (0.47) PPARDPPARAPPARG
SCHEMBL30003517 0.84 PPARD (0.37) PPARDPPARAMAPTPPARG
SCHEMBL4101642 0.82 PPARD (0.39) PPARDPPARAMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta NIPPON CHEMIPHAR CO., LTD. (JP) 2009-09-24 US disclosed
EP-1854784-A1 ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR Nippon Chemiphar Co., Ltd. (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240058-A1 Activator for Peroxisome Proliferator-Activating Receptor Delta PPARG, PPARA, PPARD HSD17B1 140/4885HSD17B2 192/4885GPR52 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.