Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.73 |
| ▸ | EGFR | P00533 | 6/20 | 0.73 |
| ▸ | GAK | O14976 | 3/20 | 0.73 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.67 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.58 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.58 |
| ▸ | STK16 | O75716 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.58 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.58 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.58 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978612 | 0.91 | SRC (0.73) | SRCEGFRGAKERBB2 | |
| SCHEMBL7673296 | 0.85 | SRC (0.74) | SRCEGFRGAKERBB2 | |
| SCHEMBL4960679 | 0.84 | MAP2K1 (0.71) | SRCEGFRGAKERBB2 | |
| SCHEMBL5251972 | 0.82 | SRC (0.80) | SRCEGFRGAKERBB2ABL1 | |
| SCHEMBL6185084 | 0.81 | SRC (0.83) | SRCEGFRGAKERBB2ABL1 | |
| SCHEMBL27537981 | 0.80 | SRC (0.73) | SRCEGFRGAKERBB2 | |
| SCHEMBL5257082 | 0.80 | SRC (0.73) | SRCEGFRGAKERBB2 | |
| SCHEMBL4078986 | 0.80 | SRC (0.75) | SRCABL1 | |
| SCHEMBL6381853 | 0.78 | EGFR (1.00) | SRCEGFRGAKERBB2 | |
| SCHEMBL6184514 | 0.78 | SRC (1.00) | SRCEGFRGAKERBB2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981505-A4 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | WYETH CORP (US) | 2009-05-13 | — | — | EP | disclosed |
| US-20090099356-A1 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | WYETH (US) | 2009-04-16 | — | — | US | disclosed |
| CN-101378758-A | Preparation of 7-alkenyl-3 quinolinecarbonitriles via a palladium mediated coupling reaction | WYETH CORP (US) | 2009-03-04 | — | — | CN | disclosed |
| EP-1981505-A2 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | Wyeth a Corporation of the State of Delaware (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007092153-A2 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | WYETH (US) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099356-A1 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | PARK7, UQCRB, PRMT7 | SRC 3605/4885EGFR 2351/4885GAK 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.