Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100729 | 0.88 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL4098458 | 0.80 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL3826160 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3826827 | 0.78 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL4095160 | 0.77 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL458211 | 0.77 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL3828806 | 0.77 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL3830863 | 0.76 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL3826564 | 0.76 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL461741 | 0.76 | PTGS2 (0.80) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059504-A1 | 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS | Rottapharm S.p.A. (IT) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008014821-A1 | 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS | ROTTAPHARM S.P.A. (IT) | 2008-02-07 | — | — | WO | disclosed |